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Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study.
Eriksen R, Perez IG, Posma JM, Haid M, Sharma S, Prehn C, Thomas LE, Koivula RW, Bizzotto R, Prehn C, Mari A, Giordano GN, Pavo I, Schwenk JM, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Rutter F, Teare H, Hansen TH, Fernandez J, Jones A, Jennison C, Walker M, McCarthy MI, Pedersen O, Ruetten H, Forgie I, Bell JD, Pearson ER, Franks PW, Adamski J, Holmes E, Frost G. Eriksen R, et al. Among authors: tsirigos kd. EBioMedicine. 2020 Aug;58:102932. doi: 10.1016/j.ebiom.2020.102932. Epub 2020 Aug 4. EBioMedicine. 2020. PMID: 32763829 Free PMC article.
Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study.
Bizzotto R, Jennison C, Jones AG, Kurbasic A, Tura A, Kennedy G, Bell JD, Thomas EL, Frost G, Eriksen R, Koivula RW, Brage S, Kaye J, Hattersley AT, Heggie A, McEvoy D, 't Hart LM, Beulens JW, Elders P, Musholt PB, Ridderstråle M, Hansen TH, Allin KH, Hansen T, Vestergaard H, Lundgaard AT, Thomsen HS, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Forgie IM, Giordano GN, Pavo I, Ruetten H, Dermitzakis E, McCarthy MI, Pedersen O, Schwenk JM, Adamski J, Franks PW, Walker M, Pearson ER, Mari A; IMI DIRECT consortium. Bizzotto R, et al. Among authors: tsirigos kd. Diabetes Care. 2021 Feb;44(2):511-518. doi: 10.2337/dc20-1567. Epub 2020 Dec 15. Diabetes Care. 2021. PMID: 33323478
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study.
Tura A, Grespan E, Göbl CS, Koivula RW, Franks PW, Pearson ER, Walker M, Forgie IM, Giordano GN, Pavo I, Ruetten H, Dermitzakis ET, McCarthy MI, Pedersen O, Schwenk JM, Adamski J, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Vangipurapu J, Cederberg H, Laakso M, Rutters F, Elders PJM, Koopman ADM, Beulens JW, Ridderstråle M, Hansen TH, Allin KH, Hansen T, Vestergaard H, Mari A; IMI DIRECT Consortium. Tura A, et al. Among authors: tsirigos kd. Diabetes. 2021 Sep;70(9):2092-2106. doi: 10.2337/db21-0227. Epub 2021 Jul 7. Diabetes. 2021. PMID: 34233929
A Brief History of Protein Sorting Prediction.
Nielsen H, Tsirigos KD, Brunak S, von Heijne G. Nielsen H, et al. Among authors: tsirigos kd. Protein J. 2019 Jun;38(3):200-216. doi: 10.1007/s10930-019-09838-3. Protein J. 2019. PMID: 31119599 Free PMC article. Review.
SignalP 5.0 improves signal peptide predictions using deep neural networks.
Almagro Armenteros JJ, Tsirigos KD, Sønderby CK, Petersen TN, Winther O, Brunak S, von Heijne G, Nielsen H. Almagro Armenteros JJ, et al. Among authors: tsirigos kd. Nat Biotechnol. 2019 Apr;37(4):420-423. doi: 10.1038/s41587-019-0036-z. Epub 2019 Feb 18. Nat Biotechnol. 2019. PMID: 30778233
SignalP 6.0 predicts all five types of signal peptides using protein language models.
Teufel F, Almagro Armenteros JJ, Johansen AR, Gíslason MH, Pihl SI, Tsirigos KD, Winther O, Brunak S, von Heijne G, Nielsen H. Teufel F, et al. Among authors: tsirigos kd. Nat Biotechnol. 2022 Jul;40(7):1023-1025. doi: 10.1038/s41587-021-01156-3. Epub 2022 Jan 3. Nat Biotechnol. 2022. PMID: 34980915 Free PMC article.
Landscape of Eukaryotic Transmembrane Beta Barrel Proteins.
Roumia AF, Theodoropoulou MC, Tsirigos KD, Nielsen H, Bagos PG. Roumia AF, et al. Among authors: tsirigos kd. J Proteome Res. 2020 Mar 6;19(3):1209-1221. doi: 10.1021/acs.jproteome.9b00740. Epub 2020 Feb 11. J Proteome Res. 2020. PMID: 32008325
Prediction of signal peptides in archaea.
Bagos PG, Tsirigos KD, Plessas SK, Liakopoulos TD, Hamodrakas SJ. Bagos PG, et al. Among authors: tsirigos kd. Protein Eng Des Sel. 2009 Jan;22(1):27-35. doi: 10.1093/protein/gzn064. Epub 2008 Nov 6. Protein Eng Des Sel. 2009. PMID: 18988691
34 results