Activated mineralocorticoid receptor regulates micro-RNA-29b in vascular smooth muscle cells.
Bretschneider M, Busch B, Mueller D, Nolze A, Schreier B, Gekle M, Grossmann C.
Bretschneider M, et al. Among authors: busch b.
FASEB J. 2016 Apr;30(4):1610-22. doi: 10.1096/fj.15-271254. Epub 2016 Jan 4.
FASEB J. 2016.
PMID: 26728178
Overall, our findings provide novel insights into the molecular mechanism of aldosterone-mediated vascular pathogenesis by identifying miR-29b as a pathophysiologic relevant target of activated MR in VSMCs and by highlighting the importance of miR processing for miR regulation.-B …
Overall, our findings provide novel insights into the molecular mechanism of aldosterone-mediated vascular pathogenesis by identifying miR-2 …