Kharel MK - Search Results

1

Drugs for Gram-Negative Bugs From 2010-2019: A Decade in Review.

Pontefract BA, Ho HT, Crain A, Kharel MK, Nybo SE. Pontefract BA, et al. Among authors: kharel mk. Open Forum Infect Dis. 2020 Jul 3;7(7):ofaa276. doi: 10.1093/ofid/ofaa276. eCollection 2020 Jul. Open Forum Infect Dis. 2020. PMID: 32760748 Free PMC article. Review.

2

Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies.

Ossai J, Khatabi B, Nybo SE, Kharel MK. Ossai J, et al. Among authors: kharel mk. J Appl Microbiol. 2022 Jan;132(1):59-77. doi: 10.1111/jam.15225. Epub 2021 Jul 29. J Appl Microbiol. 2022. PMID: 34265147 Free PMC article. Review.

3

Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters.

Kharel MK, Nybo SE, Shepherd MD, Rohr J. Kharel MK, et al. Chembiochem. 2010 Mar 1;11(4):523-32. doi: 10.1002/cbic.200900673. Chembiochem. 2010. PMID: 20140934 Free PMC article.

4

Ketoolivosyl-tetracenomycin C: a new ketosugar bearing tetracenomycin reveals new insight into the substrate flexibility of glycosyltransferase ElmGT.

Nybo SE, Shabaan KA, Kharel MK, Sutardjo H, Salas JA, Méndez C, Rohr J. Nybo SE, et al. Among authors: kharel mk. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2247-50. doi: 10.1016/j.bmcl.2012.01.094. Epub 2012 Feb 3. Bioorg Med Chem Lett. 2012. PMID: 22361136 Free PMC article.

5

Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis.

Kharel MK, Pahari P, Shepherd MD, Tibrewal N, Nybo SE, Shaaban KA, Rohr J. Kharel MK, et al. Nat Prod Rep. 2012 Feb;29(2):264-325. doi: 10.1039/c1np00068c. Epub 2011 Dec 21. Nat Prod Rep. 2012. PMID: 22186970 Free PMC article. Review.

6

Isolation of Streptomyces species from soil.

Kharel MK, Shepherd MD, Nybo SE, Smith ML, Bosserman MA, Rohr J. Kharel MK, et al. Curr Protoc Microbiol. 2010 Nov;Chapter 10:Unit 10E.4. doi: 10.1002/9780471729259.mc10e04s19. Curr Protoc Microbiol. 2010. PMID: 21053254

7

A comprehensive review of glycosylated bacterial natural products.

Elshahawi SI, Shaaban KA, Kharel MK, Thorson JS. Elshahawi SI, et al. Among authors: kharel mk. Chem Soc Rev. 2015 Nov 7;44(21):7591-697. doi: 10.1039/c4cs00426d. Chem Soc Rev. 2015. PMID: 25735878 Free PMC article. Review.

8

Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity.

Liu T, Kharel MK, Zhu L, Bright SA, Mattingly C, Adams VR, Rohr J. Liu T, et al. Among authors: kharel mk. Chembiochem. 2009 Jan 26;10(2):278-86. doi: 10.1002/cbic.200800348. Chembiochem. 2009. PMID: 19067453 Free PMC article.

9

Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate.

Kharel MK, Lian H, Rohr J. Kharel MK, et al. Org Biomol Chem. 2011 Mar 21;9(6):1799-808. doi: 10.1039/c0ob00854k. Epub 2011 Jan 24. Org Biomol Chem. 2011. PMID: 21264378 Free PMC article.

10

Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology.

Kharel MK, Rohr J. Kharel MK, et al. Curr Opin Chem Biol. 2012 Apr;16(1-2):150-61. doi: 10.1016/j.cbpa.2012.03.007. Epub 2012 Mar 30. Curr Opin Chem Biol. 2012. PMID: 22465094 Free PMC article. Review.

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