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Page 1
Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States.
Stokes T, Timmons JA, Crossland H, Tripp TR, Murphy K, McGlory C, Mitchell CJ, Oikawa SY, Morton RW, Phillips BE, Baker SK, Atherton PJ, Wahlestedt C, Phillips SM. Stokes T, et al. Among authors: crossland h. Cell Rep. 2020 Aug 4;32(5):107980. doi: 10.1016/j.celrep.2020.107980. Cell Rep. 2020. PMID: 32755574 Free PMC article. Clinical Trial.
Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism.
Wilkinson DJ, Hossain T, Hill DS, Phillips BE, Crossland H, Williams J, Loughna P, Churchward-Venne TA, Breen L, Phillips SM, Etheridge T, Rathmacher JA, Smith K, Szewczyk NJ, Atherton PJ. Wilkinson DJ, et al. Among authors: crossland h. J Physiol. 2013 Jun 1;591(11):2911-23. doi: 10.1113/jphysiol.2013.253203. Epub 2013 Apr 3. J Physiol. 2013. PMID: 23551944 Free PMC article.
A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status.
Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T, Jensen T, van Loon LJ, Lannfelt L, Kraus WE, Atherton PJ, Howard R, Gustafsson T, Hodges A, Timmons JA. Sood S, et al. Among authors: crossland h. Genome Biol. 2015 Sep 7;16(1):185. doi: 10.1186/s13059-015-0750-x. Genome Biol. 2015. PMID: 26343147 Free PMC article.
A reverse genetics cell-based evaluation of genes linked to healthy human tissue age.
Crossland H, Atherton PJ, Strömberg A, Gustafsson T, Timmons JA. Crossland H, et al. FASEB J. 2017 Jan;31(1):96-108. doi: 10.1096/fj.201600296RRR. Epub 2016 Oct 3. FASEB J. 2017. PMID: 27698205 Free PMC article.
In vitro coordination of gene expression for this in vivo tissue age signature indicates a degree of direct coordination, and the observed link with mTOR activity suggests a direct link between a robust biomarker of healthy neuromuscular age and a major axis of life span in model …
In vitro coordination of gene expression for this in vivo tissue age signature indicates a degree of direct coordination, and the observed l …
A dynamic ribosomal biogenesis response is not required for IGF-1-mediated hypertrophy of human primary myotubes.
Crossland H, Timmons JA, Atherton PJ. Crossland H, et al. FASEB J. 2017 Dec;31(12):5196-5207. doi: 10.1096/fj.201700329R. Epub 2017 Aug 3. FASEB J. 2017. PMID: 28774889 Free PMC article.
Thus, while ribosome biogenesis represents a potential site for the regulation of skeletal muscle protein synthesis and muscle mass, it does not appear to be a prerequisite for IGF-1-induced myotube hypertrophy in vitro.-Crossland, H., Timmons, J. A., Atherton, P. J …
Thus, while ribosome biogenesis represents a potential site for the regulation of skeletal muscle protein synthesis and muscle mass, it does …
Longevity-related molecular pathways are subject to midlife "switch" in humans.
Timmons JA, Volmar CH, Crossland H, Phillips BE, Sood S, Janczura KJ, Törmäkangas T, Kujala UM, Kraus WE, Atherton PJ, Wahlestedt C. Timmons JA, et al. Among authors: crossland h. Aging Cell. 2019 Aug;18(4):e12970. doi: 10.1111/acel.12970. Epub 2019 Jun 6. Aging Cell. 2019. PMID: 31168962 Free PMC article.
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