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MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression.
Luiz JPM, Toller-Kawahisa JE, Viacava PR, Nascimento DC, Pereira PT, Saraiva AL, Prado DS, LeBert M, Giurisato E, Tournier C, Cunha TM, Cunha FQ, Quesniaux V, Ryffel B, Alves-Filho JC. Luiz JPM, et al. Among authors: tournier c. J Leukoc Biol. 2020 Oct;108(4):1215-1223. doi: 10.1002/JLB.1MA0520-016R. Epub 2020 Aug 3. J Leukoc Biol. 2020. PMID: 32745297
Can tumor cells proliferate without ERK5?
Giurisato E, Tournier C. Giurisato E, et al. Among authors: tournier c. Cell Cycle. 2016;15(5):619-20. doi: 10.1080/15384101.2016.1143272. Cell Cycle. 2016. PMID: 26822978 Free PMC article. No abstract available.
Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5.
Gilbert AS, Seoane PI, Sephton-Clark P, Bojarczuk A, Hotham R, Giurisato E, Sarhan AR, Hillen A, Velde GV, Gray NS, Alessi DR, Cunningham DL, Tournier C, Johnston SA, May RC. Gilbert AS, et al. Among authors: tournier c. Sci Adv. 2017 Aug 16;3(8):e1700898. doi: 10.1126/sciadv.1700898. eCollection 2017 Aug. Sci Adv. 2017. PMID: 28835924 Free PMC article.
Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition.
Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, Finegan KG, Wang W, Wang J, Gray NS, Vermi W, Xia Z, Tournier C. Giurisato E, et al. Among authors: tournier c. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2801-E2810. doi: 10.1073/pnas.1707929115. Epub 2018 Mar 5. Proc Natl Acad Sci U S A. 2018. PMID: 29507229 Free PMC article.
Extracellular-Regulated Protein Kinase 5-Mediated Control of p21 Expression Promotes Macrophage Proliferation Associated with Tumor Growth and Metastasis.
Giurisato E, Lonardi S, Telfer B, Lussoso S, Risa-Ebrí B, Zhang J, Russo I, Wang J, Santucci A, Finegan KG, Gray NS, Vermi W, Tournier C. Giurisato E, et al. Among authors: tournier c. Cancer Res. 2020 Aug 15;80(16):3319-3330. doi: 10.1158/0008-5472.CAN-19-2416. Epub 2020 Jun 19. Cancer Res. 2020. PMID: 32561530 Free PMC article.
The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion.
Xu Q, Zhang J, Telfer BA, Zhang H, Ali N, Chen F, Risa B, Pearson AJ, Zhang W, Finegan KG, Ucar A, Giurisato E, Tournier C. Xu Q, et al. Among authors: tournier c. Oncogene. 2021 Jun;40(23):3929-3941. doi: 10.1038/s41388-021-01798-2. Epub 2021 May 12. Oncogene. 2021. PMID: 33981002 Free PMC article.
Inhibiting ERK5 overcomes breast cancer resistance to anti-HER2 therapy by targeting the G1/S cell cycle transition.
Zhang J, Pearson AJ, Sabherwal N, Telfer BA, Ali N, Kan K, Xu Q, Zhang W, Chen F, Li S, Wang J, Gray NS, Risa-Ebrí B, Finegan KG, Cross MJ, Giurisato E, Whitmarsh AJ, Tournier C. Zhang J, et al. Among authors: tournier c. Cancer Res Commun. 2022 Mar 10;2(3):131-145. doi: 10.1158/2767-9764.CRC-21-0089. Cancer Res Commun. 2022. PMID: 36466034 Free PMC article.
159 results