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A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice.
Amouyal C, Castel J, Guay C, Lacombe A, Denom J, Migrenne-Li S, Rouault C, Marquet F, Georgiadou E, Stylianides T, Luquet S, Le Stunff H, Scharfmann R, Clément K, Rutter GA, Taboureau O, Magnan C, Regazzi R, Andreelli F. Amouyal C, et al. Among authors: lacombe a. EBioMedicine. 2020 Aug;58:102895. doi: 10.1016/j.ebiom.2020.102895. Epub 2020 Jul 30. EBioMedicine. 2020. PMID: 32739864 Free PMC article.
GLUT2 accumulation in enterocyte apical and intracellular membranes: a study in morbidly obese human subjects and ob/ob and high fat-fed mice.
Ait-Omar A, Monteiro-Sepulveda M, Poitou C, Le Gall M, Cotillard A, Gilet J, Garbin K, Houllier A, Château D, Lacombe A, Veyrie N, Hugol D, Tordjman J, Magnan C, Serradas P, Clément K, Leturque A, Brot-Laroche E. Ait-Omar A, et al. Among authors: lacombe a. Diabetes. 2011 Oct;60(10):2598-607. doi: 10.2337/db10-1740. Epub 2011 Aug 18. Diabetes. 2011. PMID: 21852673 Free PMC article.
Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.
Dalmas E, Toubal A, Alzaid F, Blazek K, Eames HL, Lebozec K, Pini M, Hainault I, Montastier E, Denis RG, Ancel P, Lacombe A, Ling Y, Allatif O, Cruciani-Guglielmacci C, André S, Viguerie N, Poitou C, Stich V, Torcivia A, Foufelle F, Luquet S, Aron-Wisnewsky J, Langin D, Clément K, Udalova IA, Venteclef N. Dalmas E, et al. Among authors: lacombe a. Nat Med. 2015 Jun;21(6):610-8. doi: 10.1038/nm.3829. Epub 2015 May 4. Nat Med. 2015. PMID: 25939064
Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice.
Migrenne S, Lacombe A, Lefèvre AL, Pruniaux MP, Guillot E, Galzin AM, Magnan C. Migrenne S, et al. Among authors: lacombe a. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R929-35. doi: 10.1152/ajpregu.90824.2008. Epub 2009 Feb 11. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19211723 Free article.
Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.
Laperrousaz E, Moullé VS, Denis RG, Kassis N, Berland C, Colsch B, Fioramonti X, Philippe E, Lacombe A, Vanacker C, Butin N, Bruce KD, Wang H, Wang Y, Gao Y, Garcia-Caceres C, Prévot V, Tschöp MH, Eckel RH, Le Stunff H, Luquet S, Magnan C, Cruciani-Guglielmacci C. Laperrousaz E, et al. Among authors: lacombe a. Diabetologia. 2017 Jul;60(7):1314-1324. doi: 10.1007/s00125-017-4282-7. Epub 2017 Apr 29. Diabetologia. 2017. PMID: 28456865
Hypothalamic AgRP-neurons control peripheral substrate utilization and nutrient partitioning.
Joly-Amado A, Denis RG, Castel J, Lacombe A, Cansell C, Rouch C, Kassis N, Dairou J, Cani PD, Ventura-Clapier R, Prola A, Flamment M, Foufelle F, Magnan C, Luquet S. Joly-Amado A, et al. Among authors: lacombe a. EMBO J. 2012 Nov 14;31(22):4276-88. doi: 10.1038/emboj.2012.250. Epub 2012 Sep 18. EMBO J. 2012. PMID: 22990237 Free PMC article.
155 results