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Glial β-oxidation regulates Drosophila energy metabolism.
Schulz JG, Laranjeira A, Van Huffel L, Gärtner A, Vilain S, Bastianen J, Van Veldhoven PP, Dotti CG. Schulz JG, et al. Among authors: van veldhoven pp, van huffel l. Sci Rep. 2015 Jan 15;5:7805. doi: 10.1038/srep07805. Sci Rep. 2015. PMID: 25588812 Free PMC article.
Modulation of the Hippo pathway and organ growth by RNA processing proteins.
Mach J, Atkins M, Gajewski KM, Mottier-Pavie V, Sansores-Garcia L, Xie J, Mills RA, Kowalczyk W, Van Huffel L, Mills GB, Halder G. Mach J, et al. Among authors: van huffel l. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10684-10689. doi: 10.1073/pnas.1807325115. Epub 2018 Sep 26. Proc Natl Acad Sci U S A. 2018. PMID: 30257938 Free PMC article.
Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.
Moya IM, Castaldo SA, Van den Mooter L, Soheily S, Sansores-Garcia L, Jacobs J, Mannaerts I, Xie J, Verboven E, Hillen H, Algueró-Nadal A, Karaman R, Van Haele M, Kowalczyk W, De Waegeneer M, Verhulst S, Karras P, van Huffel L, Zender L, Marine JC, Roskams T, Johnson R, Aerts S, van Grunsven LA, Halder G. Moya IM, et al. Among authors: van grunsven la, van den mooter l, van huffel l, van haele m. Science. 2019 Nov 22;366(6468):1029-1034. doi: 10.1126/science.aaw9886. Science. 2019. PMID: 31754005
Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis.
Verboven E, Moya IM, Sansores-Garcia L, Xie J, Hillen H, Kowalczyk W, Vella G, Verhulst S, Castaldo SA, Algueró-Nadal A, Romanelli L, Mercader-Celma C, Souza NA, Soheily S, Van Huffel L, Van Brussel T, Lambrechts D, Roskams T, Lemaigre FP, Bergers G, van Grunsven LA, Halder G. Verboven E, et al. Among authors: van huffel l. Gastroenterology. 2021 Feb;160(3):847-862. doi: 10.1053/j.gastro.2020.10.035. Epub 2020 Oct 28. Gastroenterology. 2021. PMID: 33127392 Free article.
Hippo signaling instructs ectopic but not normal organ growth.
Kowalczyk W, Romanelli L, Atkins M, Hillen H, Bravo González-Blas C, Jacobs J, Xie J, Soheily S, Verboven E, Moya IM, Verhulst S, de Waegeneer M, Sansores-Garcia L, van Huffel L, Johnson RL, van Grunsven LA, Aerts S, Halder G. Kowalczyk W, et al. Among authors: van huffel l. Science. 2022 Nov 18;378(6621):eabg3679. doi: 10.1126/science.abg3679. Epub 2022 Nov 18. Science. 2022. PMID: 36395225
Advanced Hybrid Closed-Loop Therapy Compared With Standard Insulin Therapy Intrapartum and Early Postpartum in Women With Type 1 Diabetes: A Secondary Observational Analysis From the CRISTAL Randomized Controlled Trial.
Beunen K, Gillard P, Van Wilder N, Ballaux D, Vanhaverbeke G, Taes Y, Aers XP, Nobels F, Van Huffel L, Marlier J, Lee D, Cuypers J, Preumont V, Siegelaar SE, Painter RC, Laenen A, Mathieu C, Benhalima K. Beunen K, et al. Among authors: van huffel l. Diabetes Care. 2024 Nov 1;47(11):2002-2011. doi: 10.2337/dc24-1320. Diabetes Care. 2024. PMID: 39331059 Clinical Trial.
A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models.
Hillen H, Candi A, Vanderhoydonck B, Kowalczyk W, Sansores-Garcia L, Kesikiadou EC, Van Huffel L, Spiessens L, Nijs M, Soons E, Haeck W, Klaassen H, Smets W, Spieser SA, Marchand A, Chaltin P, Ciesielski F, Debaene F, Chen L, Kamal A, Gwaltney SL, Versele M, Halder GA. Hillen H, et al. Among authors: van huffel l. Mol Cancer Ther. 2024 Jan 3;23(1):3-13. doi: 10.1158/1535-7163.MCT-22-0681. Mol Cancer Ther. 2024. PMID: 37748190
18 results