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A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity.
Yang J, Wang W, Chen Z, Lu S, Yang F, Bi Z, Bao L, Mo F, Li X, Huang Y, Hong W, Yang Y, Zhao Y, Ye F, Lin S, Deng W, Chen H, Lei H, Zhang Z, Luo M, Gao H, Zheng Y, Gong Y, Jiang X, Xu Y, Lv Q, Li D, Wang M, Li F, Wang S, Wang G, Yu P, Qu Y, Yang L, Deng H, Tong A, Li J, Wang Z, Yang J, Shen G, Zhao Z, Li Y, Luo J, Liu H, Yu W, Yang M, Xu J, Wang J, Li H, Wang H, Kuang D, Lin P, Hu Z, Guo W, Cheng W, He Y, Song X, Chen C, Xue Z, Yao S, Chen L, Ma X, Chen S, Gou M, Huang W, Wang Y, Fan C, Tian Z, Shi M, Wang FS, Dai L, Wu M, Li G, Wang G, Peng Y, Qian Z, Huang C, Lau JY, Yang Z, Wei Y, Cen X, Peng X, Qin C, Zhang K, Lu G, Wei X. Yang J, et al. Among authors: wang h, wang w, wang g, wang fs, wang z, wang j, wang y, wang m, wang s. Nature. 2020 Oct;586(7830):572-577. doi: 10.1038/s41586-020-2599-8. Epub 2020 Jul 29. Nature. 2020. PMID: 32726802
Age-related rhesus macaque models of COVID-19.
Yu P, Qi F, Xu Y, Li F, Liu P, Liu J, Bao L, Deng W, Gao H, Xiang Z, Xiao C, Lv Q, Gong S, Liu J, Song Z, Qu Y, Xue J, Wei Q, Liu M, Wang G, Wang S, Yu H, Liu X, Huang B, Wang W, Zhao L, Wang H, Ye F, Zhou W, Zhen W, Han J, Wu G, Jin Q, Wang J, Tan W, Qin C. Yu P, et al. Among authors: wang h, wang g, wang w, wang j, wang s. Animal Model Exp Med. 2020 Mar 30;3(1):93-97. doi: 10.1002/ame2.12108. eCollection 2020 Mar. Animal Model Exp Med. 2020. PMID: 32318665 Free PMC article.
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice.
Bao L, Deng W, Huang B, Gao H, Liu J, Ren L, Wei Q, Yu P, Xu Y, Qi F, Qu Y, Li F, Lv Q, Wang W, Xue J, Gong S, Liu M, Wang G, Wang S, Song Z, Zhao L, Liu P, Zhao L, Ye F, Wang H, Zhou W, Zhu N, Zhen W, Yu H, Zhang X, Guo L, Chen L, Wang C, Wang Y, Wang X, Xiao Y, Sun Q, Liu H, Zhu F, Ma C, Yan L, Yang M, Han J, Xu W, Tan W, Peng X, Jin Q, Wu G, Qin C. Bao L, et al. Among authors: wang h, wang x, wang w, wang g, wang y, wang s, wang c. Nature. 2020 Jul;583(7818):830-833. doi: 10.1038/s41586-020-2312-y. Epub 2020 May 7. Nature. 2020. PMID: 32380511
Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 via Close Contact and Respiratory Droplets Among Human Angiotensin-Converting Enzyme 2 Mice.
Bao L, Gao H, Deng W, Lv Q, Yu H, Liu M, Yu P, Liu J, Qu Y, Gong S, Lin K, Qi F, Xu Y, Li F, Xiao C, Xue J, Song Z, Xiang Z, Wang G, Wang S, Liu X, Zhao W, Han Y, Wei Q, Qin C. Bao L, et al. Among authors: wang g, wang s. J Infect Dis. 2020 Jul 23;222(4):551-555. doi: 10.1093/infdis/jiaa281. J Infect Dis. 2020. PMID: 32444876 Free PMC article.
Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques.
Deng W, Bao L, Liu J, Xiao C, Liu J, Xue J, Lv Q, Qi F, Gao H, Yu P, Xu Y, Qu Y, Li F, Xiang Z, Yu H, Gong S, Liu M, Wang G, Wang S, Song Z, Liu Y, Zhao W, Han Y, Zhao L, Liu X, Wei Q, Qin C. Deng W, et al. Among authors: wang g, wang s. Science. 2020 Aug 14;369(6505):818-823. doi: 10.1126/science.abc5343. Epub 2020 Jul 2. Science. 2020. PMID: 32616673 Free PMC article.
Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in rhesus macaques.
Deng W, Bao L, Gao H, Xiang Z, Qu Y, Song Z, Gong S, Liu J, Liu J, Yu P, Qi F, Xu Y, Li F, Xiao C, Lv Q, Xue J, Wei Q, Liu M, Wang G, Wang S, Yu H, Chen T, Liu X, Zhao W, Han Y, Qin C. Deng W, et al. Among authors: wang g, wang s. Nat Commun. 2020 Sep 2;11(1):4400. doi: 10.1038/s41467-020-18149-6. Nat Commun. 2020. PMID: 32879306 Free PMC article.
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