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Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Maculins T, Garcia-Pardo J, Skenderovic A, Gebel J, Putyrski M, Vorobyov A, Busse P, Varga G, Kuzikov M, Zaliani A, Rahighi S, Schaeffer V, Parnham MJ, Sidhu SS, Ernst A, Dötsch V, Akutsu M, Dikic I. Maculins T, et al. Among authors: sidhu ss. Cell Chem Biol. 2020 Nov 19;27(11):1441-1451.e7. doi: 10.1016/j.chembiol.2020.07.010. Epub 2020 Jul 28. Cell Chem Biol. 2020. PMID: 32726587 Free article.
The multiple-specificity landscape of modular peptide recognition domains.
Gfeller D, Butty F, Wierzbicka M, Verschueren E, Vanhee P, Huang H, Ernst A, Dar N, Stagljar I, Serrano L, Sidhu SS, Bader GD, Kim PM. Gfeller D, et al. Among authors: sidhu ss. Mol Syst Biol. 2011 Apr 26;7:484. doi: 10.1038/msb.2011.18. Mol Syst Biol. 2011. PMID: 21525870 Free PMC article.
A strategy for modulation of enzymes in the ubiquitin system.
Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, Landry MC, Yeh C, Zeqiraj E, Karamboulas K, Allali-Hassani A, Vedadi M, Tyers M, Moffat J, Sicheri F, Pelletier L, Durocher D, Raught B, Rotin D, Yang J, Moran MF, Dhe-Paganon S, Sidhu SS. Ernst A, et al. Among authors: sidhu ss. Science. 2013 Feb 1;339(6119):590-5. doi: 10.1126/science.1230161. Epub 2013 Jan 3. Science. 2013. PMID: 23287719 Free PMC article.
A structural portrait of the PDZ domain family.
Ernst A, Appleton BA, Ivarsson Y, Zhang Y, Gfeller D, Wiesmann C, Sidhu SS. Ernst A, et al. Among authors: sidhu ss. J Mol Biol. 2014 Oct 23;426(21):3509-19. doi: 10.1016/j.jmb.2014.08.012. Epub 2014 Aug 23. J Mol Biol. 2014. PMID: 25158098
468 results