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Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation.
Mutlu B, Sharabi K, Sohn JH, Yuan B, Latorre-Muro P, Qin X, Yook JS, Lin H, Yu D, Camporez JPG, Kajimura S, Shulman GI, Hui S, Kamenecka TM, Griffin PR, Puigserver P. Mutlu B, et al. Among authors: yu d. Cell Chem Biol. 2025 Jan 14:S2451-9456(25)00005-4. doi: 10.1016/j.chembiol.2025.01.005. Online ahead of print. Cell Chem Biol. 2025. PMID: 39814023 No abstract available.
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