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Page 1
Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model.
Savyuk M, Krivonosov M, Mishchenko T, Gazaryan I, Ivanchenko M, Khristichenko A, Poloznikov A, Hushpulian D, Nikulin S, Tonevitsky E, Abuzarova G, Mitroshina E, Vedunova M. Savyuk M, et al. Among authors: hushpulian d. Antioxidants (Basel). 2020 Jul 24;9(8):662. doi: 10.3390/antiox9080662. Antioxidants (Basel). 2020. PMID: 32722310 Free PMC article.
Catalytic mechanism and substrate specificity of HIF prolyl hydroxylases.
Smirnova NA, Hushpulian DM, Speer RE, Gaisina IN, Ratan RR, Gazaryan IG. Smirnova NA, et al. Among authors: hushpulian dm. Biochemistry (Mosc). 2012 Oct;77(10):1108-19. doi: 10.1134/S0006297912100033. Biochemistry (Mosc). 2012. PMID: 23157291 Free article. Review.
L-ascorbic acid: A true substrate for HIF prolyl hydroxylase?
Osipyants AI, Poloznikov AA, Smirnova NA, Hushpulian DM, Khristichenko AY, Chubar TA, Zakhariants AA, Ahuja M, Gaisina IN, Thomas B, Brown AM, Gazaryan IG, Tishkov VI. Osipyants AI, et al. Biochimie. 2018 Apr;147:46-54. doi: 10.1016/j.biochi.2017.12.011. Epub 2017 Dec 28. Biochimie. 2018. PMID: 29289682 Free PMC article.
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Tapias V, Jainuddin S, Ahuja M, Stack C, Elipenahli C, Vignisse J, Gerges M, Starkova N, Xu H, Starkov AA, Bettendorff L, Hushpulian DM, Smirnova NA, Gazaryan IG, Kaidery NA, Wakade S, Calingasan NY, Thomas B, Gibson GE, Dumont M, Beal MF. Tapias V, et al. Hum Mol Genet. 2018 Aug 15;27(16):2874-2892. doi: 10.1093/hmg/ddy201. Hum Mol Genet. 2018. PMID: 29860433 Free PMC article.
29 results