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Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. Northey JJ, et al. Among authors: hansen kc. J Clin Invest. 2020 Nov 2;130(11):5721-5737. doi: 10.1172/JCI129249. J Clin Invest. 2020. PMID: 32721948 Free PMC article. Clinical Trial.
Collagen architecture in pregnancy-induced protection from breast cancer.
Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. Maller O, et al. Among authors: hansen kc. J Cell Sci. 2013 Sep 15;126(Pt 18):4108-10. doi: 10.1242/jcs.121590. Epub 2013 Jul 10. J Cell Sci. 2013. PMID: 23843613 Free PMC article.
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Laklai H, et al. Nat Med. 2016 May;22(5):497-505. doi: 10.1038/nm.4082. Epub 2016 Apr 18. Nat Med. 2016. PMID: 27089513 Free PMC article.
A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.
Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. Barnes JM, et al. Among authors: hansen kc. Nat Cell Biol. 2018 Oct;20(10):1203-1214. doi: 10.1038/s41556-018-0183-3. Epub 2018 Sep 10. Nat Cell Biol. 2018. PMID: 30202050 Free PMC article.
298 results