Moutal A - Search Results

1

Druggability of CRMP2 for Neurodegenerative Diseases.

Khanna R, Moutal A, Perez-Miller S, Chefdeville A, Boinon L, Patek M. Khanna R, et al. Among authors: moutal a. ACS Chem Neurosci. 2020 Sep 2;11(17):2492-2505. doi: 10.1021/acschemneuro.0c00307. Epub 2020 Aug 4. ACS Chem Neurosci. 2020. PMID: 32693579 Review.

2

The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth.

Wilson SM, Moutal A, Melemedjian OK, Wang Y, Ju W, François-Moutal L, Khanna M, Khanna R. Wilson SM, et al. Among authors: moutal a. Front Cell Neurosci. 2014 Jul 24;8:196. doi: 10.3389/fncel.2014.00196. eCollection 2014. Front Cell Neurosci. 2014. PMID: 25104922 Free PMC article.

3

Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides.

Moutal A, François-Moutal L, Brittain JM, Khanna M, Khanna R. Moutal A, et al. Front Cell Neurosci. 2015 Jan 26;8:471. doi: 10.3389/fncel.2014.00471. eCollection 2014. Front Cell Neurosci. 2015. PMID: 25674050 Free PMC article.

4

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.

François-Moutal L, Wang Y, Moutal A, Cottier KE, Melemedjian OK, Yang X, Wang Y, Ju W, Largent-Milnes TM, Khanna M, Vanderah TW, Khanna R. François-Moutal L, et al. Among authors: moutal a. Pain. 2015 Jul;156(7):1247-1264. doi: 10.1097/j.pain.0000000000000147. Pain. 2015. PMID: 25782368 Free PMC article.

5

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

Moutal A, François-Moutal L, Perez-Miller S, Cottier K, Chew LA, Yeon SK, Dai J, Park KD, Khanna M, Khanna R. Moutal A, et al. Mol Neurobiol. 2016 Apr;53(3):1959-1976. doi: 10.1007/s12035-015-9141-2. Epub 2015 Apr 7. Mol Neurobiol. 2016. PMID: 25846820

6

CRMP5 Controls Glioblastoma Cell Proliferation and Survival through Notch-Dependent Signaling.

Moutal A, Honnorat J, Massoma P, Désormeaux P, Bertrand C, Malleval C, Watrin C, Chounlamountri N, Mayeur ME, Besançon R, Naudet N, Magadoux L, Khanna R, Ducray F, Meyronet D, Thomasset N. Moutal A, et al. Cancer Res. 2015 Sep 1;75(17):3519-28. doi: 10.1158/0008-5472.CAN-14-0631. Epub 2015 Jun 29. Cancer Res. 2015. PMID: 26122847

7

(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.

Moutal A, Chew LA, Yang X, Wang Y, Yeon SK, Telemi E, Meroueh S, Park KD, Shrinivasan R, Gilbraith KB, Qu C, Xie JY, Patwardhan A, Vanderah TW, Khanna M, Porreca F, Khanna R. Moutal A, et al. Pain. 2016 Jul;157(7):1448-1463. doi: 10.1097/j.pain.0000000000000555. Pain. 2016. PMID: 26967696 Free PMC article.

8

Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1.

Moutal A, Dustrude ET, Khanna R. Moutal A, et al. Mol Neurobiol. 2017 Jul;54(5):3342-3349. doi: 10.1007/s12035-016-9907-1. Epub 2016 May 11. Mol Neurobiol. 2017. PMID: 27167129 Review.

9

Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential.

Xie JY, Chew LA, Yang X, Wang Y, Qu C, Wang Y, Federici LM, Fitz SD, Ripsch MS, Due MR, Moutal A, Khanna M, White FA, Vanderah TW, Johnson PL, Porreca F, Khanna R. Xie JY, et al. Among authors: moutal a. Pain. 2016 Sep;157(9):2124-2140. doi: 10.1097/j.pain.0000000000000628. Pain. 2016. PMID: 27537210 Free PMC article.

10

Efficacy of (S)-Lacosamide in preclinical models of cephalic pain.

Moutal A, Eyde N, Telemi E, Park KD, Xie JY, Dodick DW, Porreca F, Khanna R. Moutal A, et al. Pain Rep. 2016 Jun;1(1):e565. doi: 10.1097/PR9.0000000000000565. Pain Rep. 2016. PMID: 27917413 Free PMC article.

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