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Chlorine substituents and linker topology as factors of 5-HT6R activity for novel highly active 1,3,5-triazine derivatives with procognitive properties in vivo.
Sudoł S, Kucwaj-Brysz K, Kurczab R, Wilczyńska N, Jastrzębska-Więsek M, Satała G, Latacz G, Głuch-Lutwin M, Mordyl B, Żesławska E, Nitek W, Partyka A, Buzun K, Doroz-Płonka A, Wesołowska A, Bielawska A, Handzlik J. Sudoł S, et al. Among authors: nitek w. Eur J Med Chem. 2020 Oct 1;203:112529. doi: 10.1016/j.ejmech.2020.112529. Epub 2020 Jul 6. Eur J Med Chem. 2020. PMID: 32693296 Free article.
Anticonvulsant activity, crystal structures, and preliminary safety evaluation of N-trans-cinnamoyl derivatives of selected (un)modified aminoalkanols.
Gunia-Krzyżak A, Żesławska E, Słoczyńska K, Koczurkiewicz P, Nitek W, Żelaszczyk D, Szkaradek N, Waszkielewicz AM, Pękala E, Marona H. Gunia-Krzyżak A, et al. Among authors: nitek w. Eur J Med Chem. 2016 Jan 1;107:26-37. doi: 10.1016/j.ejmech.2015.10.051. Epub 2015 Nov 2. Eur J Med Chem. 2016. PMID: 26560050
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Waszkielewicz AM, Gunia-Krzyżak A, Powroźnik B, Słoczyńska K, Pękala E, Walczak M, Bednarski M, Żesławska E, Nitek W, Marona H. Waszkielewicz AM, et al. Among authors: nitek w. Bioorg Med Chem. 2016 Apr 15;24(8):1793-810. doi: 10.1016/j.bmc.2016.03.006. Epub 2016 Mar 3. Bioorg Med Chem. 2016. PMID: 26988801
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3.
Gunia-Krzyżak A, Żelaszczyk D, Rapacz A, Żesławska E, Waszkielewicz AM, Pańczyk K, Słoczyńska K, Pękala E, Nitek W, Filipek B, Marona H. Gunia-Krzyżak A, et al. Among authors: nitek w. Bioorg Med Chem. 2017 Jan 15;25(2):471-482. doi: 10.1016/j.bmc.2016.11.014. Epub 2016 Nov 11. Bioorg Med Chem. 2017. PMID: 27876250
82 results