Xu X - Search Results

1

A CFD model for predicting protein aggregation in low-pH virial inactivation for mAb production.

Xing Z, Jin W, Xu X, Song Y, Huang C, Borys MC, Ghose S, Li ZJ. Xing Z, et al. Among authors: xu x. Biotechnol Bioeng. 2020 Nov;117(11):3400-3412. doi: 10.1002/bit.27505. Epub 2020 Jul 28. Biotechnol Bioeng. 2020. PMID: 32672835

2

Disaggregation of high-molecular weight species during downstream processing to recover functional monomer.

Xu X, Didio DM, Leister KJ, Ghose S. Xu X, et al. Biotechnol Prog. 2010 May-Jun;26(3):717-26. doi: 10.1002/btpr.373. Biotechnol Prog. 2010. PMID: 20039266

3

WITHDRAWN: Aminoglycoside phosphotransferase II gene as primary selection marker for Pichia pastoris producing full-length monoclonal antibody.

Qian Y, Xu X, Qian NX, Dhar V, You L, Xing Z, Huang C, Pan SH, Li ZJ. Qian Y, et al. Among authors: xu x. Protein Expr Purif. 2012 Sep 5:S1046-5928(12)00238-0. doi: 10.1016/j.pep.2012.08.019. Online ahead of print. Protein Expr Purif. 2012. PMID: 22982086

4

Clarification and capture of high-concentration refold pools for E. coli-based therapeutics using expanded bed adsorption chromatography.

Xu X, Hirpara J, Epting K, Jin M, Ghose S, Rieble S, Li ZJ. Xu X, et al. Biotechnol Prog. 2014 Jan-Feb;30(1):113-23. doi: 10.1002/btpr.1833. Epub 2013 Nov 13. Biotechnol Prog. 2014. PMID: 24167114

5

Adaptation of the pore diffusion model to describe multi-addition batch uptake high-throughput screening experiments.

Traylor SJ, Xu X, Li Y, Jin M, Li ZJ. Traylor SJ, et al. Among authors: xu x. J Chromatogr A. 2014 Nov 14;1368:100-6. doi: 10.1016/j.chroma.2014.09.058. Epub 2014 Sep 30. J Chromatogr A. 2014. PMID: 25311484

6

Heterogeneous glycoform separation by process chromatography: I: Monomer purification and characterization.

Li Y, Xu X, Shupe A, Yang R, Bai K, Das T, Borys MC, Li ZJ. Li Y, et al. Among authors: xu x. J Chromatogr A. 2015 Jul 24;1404:51-9. doi: 10.1016/j.chroma.2015.05.054. Epub 2015 May 28. J Chromatogr A. 2015. PMID: 26051082

7

Insights in understanding aggregate formation and dissociation in cation exchange chromatography for a structurally unstable Fc-fusion protein.

Chen Z, Huang C, Chennamsetty N, Xu X, Li ZJ. Chen Z, et al. Among authors: xu x. J Chromatogr A. 2016 Aug 19;1460:110-22. doi: 10.1016/j.chroma.2016.07.023. Epub 2016 Jul 9. J Chromatogr A. 2016. PMID: 27452990

8

Conformation Preservation of α-Helical Peptides within Supramolecular Filamentous Assemblies.

Li Y, Wang Y, Ou SH, Lock LL, Xu X, Ghose S, Li ZJ, Cui H. Li Y, et al. Among authors: xu x. Biomacromolecules. 2017 Nov 13;18(11):3611-3620. doi: 10.1021/acs.biomac.7b00992. Epub 2017 Sep 27. Biomacromolecules. 2017. PMID: 28891286

9

One-step affinity capture and precipitation for improved purification of an industrial monoclonal antibody using Z-ELP functionalized nanocages.

Swartz AR, Xu X, Traylor SJ, Li ZJ, Chen W. Swartz AR, et al. Among authors: xu x. Biotechnol Bioeng. 2018 Feb;115(2):423-432. doi: 10.1002/bit.26467. Epub 2017 Oct 30. Biotechnol Bioeng. 2018. PMID: 28986999

10

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media.

Xu J, Rehmann MS, Xu X, Huang C, Tian J, Qian NX, Li ZJ. Xu J, et al. Among authors: xu x. MAbs. 2018 Apr;10(3):488-499. doi: 10.1080/19420862.2018.1433978. Epub 2018 Feb 20. MAbs. 2018. PMID: 29388872 Free PMC article.

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