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PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response.
Aberle L, Krüger A, Reber JM, Lippmann M, Hufnagel M, Schmalz M, Trussina IREA, Schlesiger S, Zubel T, Schütz K, Marx A, Hartwig A, Ferrando-May E, Bürkle A, Mangerich A. Aberle L, et al. Among authors: zubel t. Nucleic Acids Res. 2020 Oct 9;48(18):10015-10033. doi: 10.1093/nar/gkaa590. Nucleic Acids Res. 2020. PMID: 32667640 Free PMC article.
Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.
Rank L, Veith S, Gwosch EC, Demgenski J, Ganz M, Jongmans MC, Vogel C, Fischbach A, Buerger S, Fischer JM, Zubel T, Stier A, Renner C, Schmalz M, Beneke S, Groettrup M, Kuiper RP, Bürkle A, Ferrando-May E, Mangerich A. Rank L, et al. Among authors: zubel t. Nucleic Acids Res. 2016 Dec 1;44(21):10386-10405. doi: 10.1093/nar/gkw859. Epub 2016 Sep 29. Nucleic Acids Res. 2016. PMID: 27694308 Free PMC article.
Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.
Schuhwerk H, Bruhn C, Siniuk K, Min W, Erener S, Grigaravicius P, Krüger A, Ferrari E, Zubel T, Lazaro D, Monajembashi S, Kiesow K, Kroll T, Bürkle A, Mangerich A, Hottiger M, Wang ZQ. Schuhwerk H, et al. Among authors: zubel t. Nucleic Acids Res. 2017 Nov 2;45(19):11174-11192. doi: 10.1093/nar/gkx717. Nucleic Acids Res. 2017. PMID: 28977496 Free PMC article.
The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans.
Neumann C, Baesler J, Steffen G, Nicolai MM, Zubel T, Aschner M, Bürkle A, Mangerich A, Schwerdtle T, Bornhorst J. Neumann C, et al. Among authors: zubel t. J Trace Elem Med Biol. 2020 Jan;57:21-27. doi: 10.1016/j.jtemb.2019.09.001. Epub 2019 Sep 14. J Trace Elem Med Biol. 2020. PMID: 31546209 Free PMC article.
11 results