Díaz JF - Search Results

1

Structural Basis of Noscapine Activation for Tubulin Binding.

Oliva MA, Prota AE, Rodríguez-Salarichs J, Bennani YL, Jiménez-Barbero J, Bargsten K, Canales Á, Steinmetz MO, Díaz JF. Oliva MA, et al. Among authors: diaz jf. J Med Chem. 2020 Aug 13;63(15):8495-8501. doi: 10.1021/acs.jmedchem.0c00855. Epub 2020 Jul 29. J Med Chem. 2020. PMID: 32657585 Free article.

2

Control of the structural stability of the tubulin dimer by one high affinity bound magnesium ion at nucleotide N-site.

Menéndez M, Rivas G, Díaz JF, Andreu JM. Menéndez M, et al. Among authors: diaz jf. J Biol Chem. 1998 Jan 2;273(1):167-76. doi: 10.1074/jbc.273.1.167. J Biol Chem. 1998. PMID: 9417061 Free article.

3

Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity.

Buey RM, Barasoain I, Jackson E, Meyer A, Giannakakou P, Paterson I, Mooberry S, Andreu JM, Díaz JF. Buey RM, et al. Among authors: diaz jf. Chem Biol. 2005 Dec;12(12):1269-79. doi: 10.1016/j.chembiol.2005.09.010. Chem Biol. 2005. PMID: 16356844

4

NMR determination of the bioactive conformation of peloruside A bound to microtubules.

Jiménez-Barbero J, Canales A, Northcote PT, Buey RM, Andreu JM, Díaz JF. Jiménez-Barbero J, et al. Among authors: diaz jf. J Am Chem Soc. 2006 Jul 12;128(27):8757-65. doi: 10.1021/ja0580237. J Am Chem Soc. 2006. PMID: 16819869

5

Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.

La Regina G, Edler MC, Brancale A, Kandil S, Coluccia A, Piscitelli F, Hamel E, De Martino G, Matesanz R, Díaz JF, Scovassi AI, Prosperi E, Lavecchia A, Novellino E, Artico M, Silvestri R. La Regina G, et al. Among authors: diaz jf. J Med Chem. 2007 Jun 14;50(12):2865-74. doi: 10.1021/jm061479u. Epub 2007 May 12. J Med Chem. 2007. PMID: 17497841

6

The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin.

Canales A, Matesanz R, Gardner NM, Andreu JM, Paterson I, Díaz JF, Jiménez-Barbero J. Canales A, et al. Among authors: diaz jf. Chemistry. 2008;14(25):7557-69. doi: 10.1002/chem.200800039. Chemistry. 2008. PMID: 18449868

7

Probing the pore drug binding site of microtubules with fluorescent taxanes: evidence of two binding poses.

Barasoain I, García-Carril AM, Matesanz R, Maccari G, Trigili C, Mori M, Shi JZ, Fang WS, Andreu JM, Botta M, Díaz JF. Barasoain I, et al. Among authors: diaz jf. Chem Biol. 2010 Mar 26;17(3):243-53. doi: 10.1016/j.chembiol.2010.02.006. Chem Biol. 2010. PMID: 20338516

8

Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity.

Pera B, Razzak M, Trigili C, Pineda O, Canales A, Buey RM, Jiménez-Barbero J, Northcote PT, Paterson I, Barasoain I, Díaz JF. Pera B, et al. Among authors: diaz jf. Chembiochem. 2010 Aug 16;11(12):1669-78. doi: 10.1002/cbic.201000294. Chembiochem. 2010. PMID: 20665616

9

Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules.

Marco JA, García-Pla J, Carda M, Murga J, Falomir E, Trigili C, Notararigo S, Díaz JF, Barasoain I. Marco JA, et al. Among authors: diaz jf. Eur J Med Chem. 2011 May;46(5):1630-7. doi: 10.1016/j.ejmech.2011.02.011. Epub 2011 Feb 22. Eur J Med Chem. 2011. PMID: 21396747

10

Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.

Canales A, Rodríguez-Salarichs J, Trigili C, Nieto L, Coderch C, Andreu JM, Paterson I, Jiménez-Barbero J, Díaz JF. Canales A, et al. Among authors: diaz jf. ACS Chem Biol. 2011 Aug 19;6(8):789-99. doi: 10.1021/cb200099u. Epub 2011 May 13. ACS Chem Biol. 2011. PMID: 21539341 Free article.

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