McLaughlin SH - Search Results

1

Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.

Chang L, Yang J, Jo CH, Boland A, Zhang Z, McLaughlin SH, Abu-Thuraia A, Killoran RC, Smith MJ, Côté JF, Barford D. Chang L, et al. Among authors: mclaughlin sh. Nat Commun. 2020 Jul 10;11(1):3464. doi: 10.1038/s41467-020-17271-9. Nat Commun. 2020. PMID: 32651375 Free PMC article.

2

Molecular architecture and mechanism of the anaphase-promoting complex.

Chang LF, Zhang Z, Yang J, McLaughlin SH, Barford D. Chang LF, et al. Among authors: mclaughlin sh. Nature. 2014 Sep 18;513(7518):388-393. doi: 10.1038/nature13543. Epub 2014 Jul 20. Nature. 2014. PMID: 25043029 Free PMC article.

3

Atomic structure of the APC/C and its mechanism of protein ubiquitination.

Chang L, Zhang Z, Yang J, McLaughlin SH, Barford D. Chang L, et al. Among authors: mclaughlin sh. Nature. 2015 Jun 25;522(7557):450-454. doi: 10.1038/nature14471. Epub 2015 Jun 15. Nature. 2015. PMID: 26083744 Free PMC article.

4

Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi.

Galindo A, Soler N, McLaughlin SH, Yu M, Williams RL, Munro S. Galindo A, et al. Among authors: mclaughlin sh. Cell Rep. 2016 Jul 19;16(3):839-50. doi: 10.1016/j.celrep.2016.06.022. Epub 2016 Jun 30. Cell Rep. 2016. PMID: 27373159 Free PMC article.

5

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.

Liu Y, Gupta GD, Barnabas DD, Agircan FG, Mehmood S, Wu D, Coyaud E, Johnson CM, McLaughlin SH, Andreeva A, Freund SMV, Robinson CV, Cheung SWT, Raught B, Pelletier L, van Breugel M. Liu Y, et al. Among authors: mclaughlin sh. Nat Commun. 2018 Apr 30;9(1):1731. doi: 10.1038/s41467-018-04122-x. Nat Commun. 2018. PMID: 29712910 Free PMC article.

6

Architecture of the CBF3-centromere complex of the budding yeast kinetochore.

Yan K, Zhang Z, Yang J, McLaughlin SH, Barford D. Yan K, et al. Among authors: mclaughlin sh. Nat Struct Mol Biol. 2018 Dec;25(12):1103-1110. doi: 10.1038/s41594-018-0154-1. Epub 2018 Nov 26. Nat Struct Mol Biol. 2018. PMID: 30478265 Free PMC article.

7

Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.

Yan K, Yang J, Zhang Z, McLaughlin SH, Chang L, Fasci D, Ehrenhofer-Murray AE, Heck AJR, Barford D. Yan K, et al. Among authors: mclaughlin sh. Nature. 2019 Oct;574(7777):278-282. doi: 10.1038/s41586-019-1609-1. Epub 2019 Oct 2. Nature. 2019. PMID: 31578520 Free PMC article.

8

A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.

Kiss L, Zeng J, Dickson CF, Mallery DL, Yang JC, McLaughlin SH, Boland A, Neuhaus D, James LC. Kiss L, et al. Among authors: mclaughlin sh. Nat Commun. 2019 Oct 3;10(1):4502. doi: 10.1038/s41467-019-12388-y. Nat Commun. 2019. PMID: 31582740 Free PMC article.

9

Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.

Fischer ES, Yu CWH, Bellini D, McLaughlin SH, Orr CM, Wagner A, Freund SMV, Barford D. Fischer ES, et al. Among authors: mclaughlin sh. EMBO Rep. 2021 Jul 5;22(7):e52242. doi: 10.15252/embr.202052242. Epub 2021 May 19. EMBO Rep. 2021. PMID: 34013668 Free PMC article.

10

Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.

Heimhalt M, Berndt A, Wagstaff J, Anandapadamanaban M, Perisic O, Maslen S, McLaughlin S, Yu CW, Masson GR, Boland A, Ni X, Yamashita K, Murshudov GN, Skehel M, Freund SM, Williams RL. Heimhalt M, et al. Elife. 2021 Sep 14;10:e68799. doi: 10.7554/eLife.68799. Elife. 2021. PMID: 34519269 Free PMC article.

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