Werman JM - Search Results

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Post-translational Succinylation of Mycobacterium tuberculosis Enoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA.

Bonds AC, Yuan T, Werman JM, Jang J, Lu R, Nesbitt NM, Garcia-Diaz M, Sampson NS. Bonds AC, et al. Among authors: werman jm. ACS Infect Dis. 2020 Aug 14;6(8):2214-2224. doi: 10.1021/acsinfecdis.0c00329. Epub 2020 Jul 27. ACS Infect Dis. 2020. PMID: 32649175 Free PMC article.

Enzymatic β-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA.

Yuan T, Werman JM, Yin X, Yang M, Garcia-Diaz M, Sampson NS. Yuan T, et al. Among authors: werman jm. ACS Infect Dis. 2021 Jun 11;7(6):1739-1751. doi: 10.1021/acsinfecdis.1c00069. Epub 2021 Apr 7. ACS Infect Dis. 2021. PMID: 33826843 Free PMC article.

The pursuit of mechanism of action: uncovering drug complexity in TB drug discovery.

Yuan T, Werman JM, Sampson NS. Yuan T, et al. Among authors: werman jm. RSC Chem Biol. 2021 Apr 1;2(2):423-440. doi: 10.1039/d0cb00226g. Epub 2021 Jan 13. RSC Chem Biol. 2021. PMID: 33928253 Free PMC article.

A Chemoproteomic Approach to Elucidate the Mechanism of Action of 6-Azasteroids with Unique Activity in Mycobacteria.

Werman JM, Chen YC, Yuan T, Yang X, Sampson NS. Werman JM, et al. ACS Infect Dis. 2023 Oct 13;9(10):1993-2004. doi: 10.1021/acsinfecdis.3c00296. Epub 2023 Sep 29. ACS Infect Dis. 2023. PMID: 37774412 Free PMC article.

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