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Mycophenolic acid and 6-mercaptopurine both inhibit B-cell proliferation in granulomatosis with polyangiitis patients, whereas only mycophenolic acid inhibits B-cell IL-6 production.
von Borstel A, Abdulahad WH, Dekkema G, Rutgers A, Stegeman CA, Veldman J, Heeringa P, Sanders JS. von Borstel A, et al. Among authors: sanders js. PLoS One. 2020 Jul 9;15(7):e0235743. doi: 10.1371/journal.pone.0235743. eCollection 2020. PLoS One. 2020. PMID: 32645052 Free PMC article.
Towards precision medicine in ANCA-associated vasculitis.
van der Geest KSM, Brouwer E, Sanders JS, Sandovici M, Bos NA, Boots AMH, Abdulahad WH, Stegeman CA, Kallenberg CGM, Heeringa P, Rutgers A. van der Geest KSM, et al. Among authors: sanders js. Rheumatology (Oxford). 2018 Aug 1;57(8):1332-1339. doi: 10.1093/rheumatology/kex367. Rheumatology (Oxford). 2018. PMID: 29045715 Review.
Review: What Is the Current Evidence for Disease Subsets in Giant Cell Arteritis?
van der Geest KSM, Sandovici M, van Sleen Y, Sanders JS, Bos NA, Abdulahad WH, Stegeman CA, Heeringa P, Rutgers A, Kallenberg CGM, Boots AMH, Brouwer E. van der Geest KSM, et al. Among authors: sanders js. Arthritis Rheumatol. 2018 Sep;70(9):1366-1376. doi: 10.1002/art.40520. Epub 2018 Jul 30. Arthritis Rheumatol. 2018. PMID: 29648680 Free PMC article. Review.
Evidence for enhanced Bruton's tyrosine kinase activity in transitional and naïve B cells of patients with granulomatosis with polyangiitis.
von Borstel A, Abdulahad WH, Sanders JS, Rip J, Neys SFH, Hendriks RW, Stegeman CA, Heeringa P, Rutgers A, Corneth OBJ. von Borstel A, et al. Among authors: sanders js. Rheumatology (Oxford). 2019 Dec 1;58(12):2230-2239. doi: 10.1093/rheumatology/kez205. Rheumatology (Oxford). 2019. PMID: 31209475 Free PMC article.
Mycophenolate Mofetil Versus Cyclophosphamide for the Induction of Remission in Nonlife-Threatening Relapses of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Randomized, Controlled Trial.
Tuin J, Stassen PM, Bogdan DI, Broekroelofs J, van Paassen P, Cohen Tervaert JW, Sanders JS, Stegeman CA. Tuin J, et al. Among authors: sanders js. Clin J Am Soc Nephrol. 2019 Jul 5;14(7):1021-1028. doi: 10.2215/CJN.11801018. Epub 2019 Jun 28. Clin J Am Soc Nephrol. 2019. PMID: 31253599 Free PMC article. Clinical Trial.
246 results