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Page 1
Safety, Pharmacokinetics, and Causal Prophylactic Efficacy of KAF156 in a Plasmodium falciparum Human Infection Study.
Kublin JG, Murphy SC, Maenza J, Seilie AM, Jain JP, Berger D, Spera D, Zhao R, Soon RL, Czartoski JL, Potochnic MA, Duke E, Chang M, Vaughan A, Kappe SHI, Leong FJ, Pertel P, Prince WT; KAF156 Study Team. Kublin JG, et al. Among authors: murphy sc. Clin Infect Dis. 2021 Oct 5;73(7):e2407-e2414. doi: 10.1093/cid/ciaa952. Clin Infect Dis. 2021. PMID: 32644127 Free PMC article. Clinical Trial.
External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance.
Murphy SC, Hermsen CC, Douglas AD, Edwards NJ, Petersen I, Fahle GA, Adams M, Berry AA, Billman ZP, Gilbert SC, Laurens MB, Leroy O, Lyke KE, Plowe CV, Seilie AM, Strauss KA, Teelen K, Hill AV, Sauerwein RW. Murphy SC, et al. PLoS One. 2014 May 16;9(5):e97398. doi: 10.1371/journal.pone.0097398. eCollection 2014. PLoS One. 2014. PMID: 24838112 Free PMC article.
Safety and comparability of controlled human Plasmodium falciparum infection by mosquito bite in malaria-naïve subjects at a new facility for sporozoite challenge.
Talley AK, Healy SA, Finney OC, Murphy SC, Kublin J, Salas CJ, Lundebjerg S, Gilbert P, Van Voorhis WC, Whisler J, Wang R, Ockenhouse CF, Heppner DG, Kappe SH, Duffy PE. Talley AK, et al. Among authors: murphy sc. PLoS One. 2014 Nov 18;9(11):e109654. doi: 10.1371/journal.pone.0109654. eCollection 2014. PLoS One. 2014. PMID: 25405724 Free PMC article. Clinical Trial.
Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies.
Hodgson SH, Douglas AD, Edwards NJ, Kimani D, Elias SC, Chang M, Daza G, Seilie AM, Magiri C, Muia A, Juma EA, Cole AO, Rampling TW, Anagnostou NA, Gilbert SC, Hoffman SL, Draper SJ, Bejon P, Ogutu B, Marsh K, Hill AV, Murphy SC. Hodgson SH, et al. Among authors: murphy sc. Malar J. 2015 Jan 28;14:33. doi: 10.1186/s12936-015-0541-6. Malar J. 2015. PMID: 25627033 Free PMC article.
Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.
Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JCC, Murphy SC, Kappe SHI, Kaushansky A. Douglass AN, et al. Among authors: murphy sc. Mol Ther. 2015 May;23(5):857-865. doi: 10.1038/mt.2015.18. Epub 2015 Feb 4. Mol Ther. 2015. PMID: 25648263 Free PMC article.
Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects.
Kublin JG, Mikolajczak SA, Sack BK, Fishbaugher ME, Seilie A, Shelton L, VonGoedert T, Firat M, Magee S, Fritzen E, Betz W, Kain HS, Dankwa DA, Steel RW, Vaughan AM, Noah Sather D, Murphy SC, Kappe SH. Kublin JG, et al. Among authors: murphy sc. Sci Transl Med. 2017 Jan 4;9(371):eaad9099. doi: 10.1126/scitranslmed.aad9099. Sci Transl Med. 2017. PMID: 28053159 Clinical Trial.
167 results