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A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies.
Acharya P, Williams W, Henderson R, Janowska K, Manne K, Parks R, Deyton M, Sprenz J, Stalls V, Kopp M, Mansouri K, Edwards RJ, Meyerhoff RR, Oguin T, Sempowski G, Saunders K, Haynes BF. Acharya P, et al. Among authors: henderson r. bioRxiv [Preprint]. 2020 Jun 30:2020.06.30.178897. doi: 10.1101/2020.06.30.178897. bioRxiv. 2020. PMID: 32637953 Free PMC article. Preprint.
Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.
Bonsignori M, Scott E, Wiehe K, Easterhoff D, Alam SM, Hwang KK, Cooper M, Xia SM, Zhang R, Montefiori DC, Henderson R, Nie X, Kelsoe G, Moody MA, Chen X, Joyce MG, Kwong PD, Connors M, Mascola JR, McGuire AT, Stamatatos L, Medina-Ramírez M, Sanders RW, Saunders KO, Kepler TB, Haynes BF. Bonsignori M, et al. Among authors: henderson r. Immunity. 2018 Dec 18;49(6):1162-1174.e8. doi: 10.1016/j.immuni.2018.10.015. Epub 2018 Dec 11. Immunity. 2018. PMID: 30552024 Free PMC article.
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche CC, Henderson R, Hsu A, Behrens S, Chen X, Zhou T, Wiehe K, Saunders KO, Alam SM, Bonsignori M, Borgnia MJ, Sattentau QJ, Eaton A, Greene K, Gao H, Liao HX, Williams WB, Peacock J, Tang H, Perez LG, Edwards RJ, Kepler TB, Korber BT, Kwong PD, Mascola JR, Acharya P, Haynes BF, Montefiori DC. LaBranche CC, et al. Among authors: henderson r. PLoS Pathog. 2019 Sep 17;15(9):e1008026. doi: 10.1371/journal.ppat.1008026. eCollection 2019 Sep. PLoS Pathog. 2019. PMID: 31527908 Free PMC article.
Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche CC, Henderson R, Hsu A, Behrens S, Chen X, Zhou T, Wiehe K, Saunders KO, Alam SM, Bonsignori M, Borgnia MJ, Sattentau QJ, Eaton A, Greene K, Gao H, Liao HX, Williams WB, Peacock J, Tang H, Perez LG, Edwards RJ, Kepler TB, Korber BT, Kwong PD, Mascola JR, Acharya P, Haynes BF, Montefiori DC. LaBranche CC, et al. Among authors: henderson r. PLoS Pathog. 2019 Dec 2;15(12):e1008200. doi: 10.1371/journal.ppat.1008200. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31790514 Free PMC article.
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.
Henderson R, Lu M, Zhou Y, Mu Z, Parks R, Han Q, Hsu AL, Carter E, Blanchard SC, Edwards RJ, Wiehe K, Saunders KO, Borgnia MJ, Bartesaghi A, Mothes W, Haynes BF, Acharya P, Munir Alam S. Henderson R, et al. Nat Commun. 2020 Jan 24;11(1):520. doi: 10.1038/s41467-019-14196-w. Nat Commun. 2020. PMID: 31980614 Free PMC article.
Controlling the SARS-CoV-2 spike glycoprotein conformation.
Henderson R, Edwards RJ, Mansouri K, Janowska K, Stalls V, Gobeil SMC, Kopp M, Li D, Parks R, Hsu AL, Borgnia MJ, Haynes BF, Acharya P. Henderson R, et al. Nat Struct Mol Biol. 2020 Oct;27(10):925-933. doi: 10.1038/s41594-020-0479-4. Epub 2020 Jul 22. Nat Struct Mol Biol. 2020. PMID: 32699321 Free PMC article.
Cold sensitivity of the SARS-CoV-2 spike ectodomain.
Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Janowska K, Gobeil SMC, Kopp M, Li D, Lu X, Mu Z, Deyton M, Oguin TH, Sprenz J, Williams W, Saunders K, Montefiori D, Sempowski GD, Henderson R, Alam M, Haynes BF, Acharya P. Edwards RJ, et al. Among authors: henderson r. bioRxiv [Preprint]. 2020 Oct 13:2020.07.12.199588. doi: 10.1101/2020.07.12.199588. bioRxiv. 2020. Update in: Nat Struct Mol Biol. 2021 Feb;28(2):128-131. doi: 10.1038/s41594-020-00547-5 PMID: 32699852 Free PMC article. Updated. Preprint.
2,967 results