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Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction.
Strizhak AV, Babii O, Afonin S, Bakanovich I, Pantelejevs T, Xu W, Fowler E, Eapen R, Sharma K, Platonov MO, Hurmach VV, Itzhaki L, Hyvönen M, Ulrich AS, Spring DR, Komarov IV. Strizhak AV, et al. Among authors: hurmach vv. Org Biomol Chem. 2020 Jul 22;18(28):5359-5369. doi: 10.1039/d0ob00831a. Org Biomol Chem. 2020. PMID: 32390036 Free article.
Synthesis, biological evaluation, and modeling studies of 1,3-disubstituted cyclobutane-containing analogs of combretastatin A4.
Malashchuk A, Chernykh AV, Hurmach VV, Platonov MO, Onopchenko O, Zozulya S, Daniliuc CG, Dobrydnev AV, Kondratov IS, Moroz YS, Grygorenko OO. Malashchuk A, et al. Among authors: hurmach vv. J Mol Struct. 2020 Jun 15;1210:128025. doi: 10.1016/j.molstruc.2020.128025. Epub 2020 May 10. J Mol Struct. 2020. PMID: 32655187 Free PMC article.
Integrated workflow for the identification of new GABAA R positive allosteric modulators based on the in silico screening with further in vitro validation. Case study using Enamine's stock chemical space.
Platonov M, Maximyuk O, Rayevsky A, Iegorova O, Hurmach V, Holota Y, Bulgakov E, Cherninskyi A, Karpov P, Ryabukhin S, Krishtal O, Volochnyuk D. Platonov M, et al. Among authors: hurmach v. Mol Inform. 2024 Feb;43(2):e202300156. doi: 10.1002/minf.202300156. Epub 2024 Jan 24. Mol Inform. 2024. PMID: 37964718
22 results