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Page 1
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target.
Franses JW, Philipp J, Missios P, Bhan I, Liu A, Yashaswini C, Tai E, Zhu H, Ligorio M, Nicholson B, Tassoni EM, Desai N, Kulkarni AS, Szabolcs A, Hong TS, Liss AS, Fernandez-Del Castillo C, Ryan DP, Maheswaran S, Haber DA, Daley GQ, Ting DT. Franses JW, et al. Among authors: missios p. Nat Commun. 2020 Jul 3;11(1):3303. doi: 10.1038/s41467-020-17150-3. Nat Commun. 2020. PMID: 32620742 Free PMC article.
LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy.
Missios P, da Rocha EL, Pearson DS, Philipp J, Aleman MM, Pirouz M, Farache D, Franses JW, Kubaczka C, Tsanov KM, Jha DK, Pepe-Mooney B, Powers JT, Gregory RI, Lee AS, Dominguez D, Ting DT, Daley GQ. Missios P, et al. J Clin Invest. 2021 Nov 15;131(22):e145142. doi: 10.1172/JCI145142. J Clin Invest. 2021. PMID: 34779407 Free PMC article.
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors.
Tao T, Shi H, Mariani L, Abraham BJ, Durbin AD, Zimmerman MW, Powers JT, Missios P, Ross KN, Perez-Atayde AR, Bulyk ML, Young RA, Daley GQ, Look AT. Tao T, et al. Among authors: missios p. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16516-16526. doi: 10.1073/pnas.1922692117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601179 Free PMC article.
Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer.
Eser PÖ, Paranal RM, Son J, Ivanova E, Kuang Y, Haikala HM, To C, Okoro JJ, Dholakia KH, Choi J, Eum Y, Ogino A, Missios P, Ercan D, Xu M, Poitras MJ, Wang S, Ngo K, Dills M, Yanagita M, Lopez T, Lin M, Tsai J, Floch N, Chambers ES, Heng J, Anjum R, Santucci AD, Michael K, Schuller AG, Cross D, Smith PD, Oxnard GR, Barbie DA, Sholl LM, Bahcall M, Palakurthi S, Gokhale PC, Paweletz CP, Daley GQ, Jänne PA. Eser PÖ, et al. Among authors: missios p. Sci Transl Med. 2021 Sep;13(609):eabb3738. doi: 10.1126/scitranslmed.abb3738. Epub 2021 Sep 1. Sci Transl Med. 2021. PMID: 34516823 Free PMC article.
Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma.
Bitzer M, Spahn S, Babaei S, Horger M, Singer S, Schulze-Osthoff K, Missios P, Gatidis S, Nann D, Mattern S, Scheble V, Nikolaou K, Armeanu-Ebinger S, Schulze M, Schroeder C, Biskup S, Beha J, Claassen M, Ruhm K, Poso A, Malek NP. Bitzer M, et al. Among authors: missios p. NPJ Precis Oncol. 2021 Sep 3;5(1):80. doi: 10.1038/s41698-021-00220-0. NPJ Precis Oncol. 2021. PMID: 34480077 Free PMC article.
[The molecular tumor board].
Missios P, Beha J, Bitzer M, Malek NP. Missios P, et al. Chirurg. 2021 Nov;92(11):1011-1015. doi: 10.1007/s00104-021-01487-6. Chirurg. 2021. PMID: 34406439 Review. German.