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Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature. 2020 Aug;584(7822):614-618. doi: 10.1038/s41586-020-2443-1. Epub 2020 Jul 1.
Nature. 2020.
PMID: 32612233
Free PMC article.
Clinical Trial.
A small-molecule inhibitor of hepatitis C virus infectivity.
Bush CO, Pokrovskii MV, Saito R, Morganelli P, Canales E, Clarke MO, Lazerwith SE, Golde J, Reid BG, Babaoglu K, Pagratis N, Zhong W, Delaney WE 4th, Paulson MS, Beran RK.
Bush CO, et al.
Antimicrob Agents Chemother. 2014;58(1):386-96. doi: 10.1128/AAC.02083-13. Epub 2013 Oct 28.
Antimicrob Agents Chemother. 2014.
PMID: 24165192
Free PMC article.
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Discovery of Hepatitis B Virus Surface Antigen Suppressor GS-8873.
Kato D, Choy RW, Canales E, Dick RA, Lake AD, Shapiro ND, Chin E, Li J, Zhang JR, Wu Q, Saito RD, Metobo S, Aktoudianakis E, Schroeder SD, Yang ZY, Glatt DM, Balsitis S, Gamelin L, Yu M, Cheng G, Delaney WE 4th, Link JO.
Kato D, et al. Among authors: saito rd.
ACS Med Chem Lett. 2024 Mar 22;15(4):546-554. doi: 10.1021/acsmedchemlett.4c00037. eCollection 2024 Apr 11.
ACS Med Chem Lett. 2024.
PMID: 38628802
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A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression.
Baird JR, Alice AF, Saito R, Chai Q, Han M, Ng C, Han S, Fernandez B, Ledoux S, Grosse J, Korman AJ, Potuznik M, Rajamanickam V, Bernard B, Crittenden MR, Gough MJ.
Baird JR, et al.
Sci Rep. 2024 Dec 2;14(1):29913. doi: 10.1038/s41598-024-80677-8.
Sci Rep. 2024.
PMID: 39622844
Free PMC article.
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