Coskun E - Search Results

1

Expression of a germline variant in the N-terminal domain of the human DNA glycosylase NTHL1 induces cellular transformation without impairing enzymatic function or substrate specificity.

Marsden CG, Jaruga P, Coskun E, Maher RL, Pederson DS, Dizdaroglu M, Sweasy JB. Marsden CG, et al. Among authors: coskun e. Oncotarget. 2020 Jun 16;11(24):2262-2272. doi: 10.18632/oncotarget.27548. eCollection 2020 Jun 16. Oncotarget. 2020. PMID: 32595826 Free PMC article.

2

Polymorphic variant Asp239Tyr of human DNA glycosylase NTHL1 is inactive for removal of a variety of oxidatively-induced DNA base lesions from genomic DNA.

Kant M, Quintana V, Coskun E, Jaruga P, Lloyd RS, Sweasy JB, Dizdaroglu M. Kant M, et al. Among authors: coskun e. DNA Repair (Amst). 2022 Sep;117:103372. doi: 10.1016/j.dnarep.2022.103372. Epub 2022 Jul 16. DNA Repair (Amst). 2022. PMID: 35870279

3

Measurement of oxidatively induced DNA damage and its repair, by mass spectrometric techniques.

Dizdaroglu M, Coskun E, Jaruga P. Dizdaroglu M, et al. Among authors: coskun e. Free Radic Res. 2015 May;49(5):525-48. doi: 10.3109/10715762.2015.1014814. Epub 2015 Mar 27. Free Radic Res. 2015. PMID: 25812590 Review.

4

Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1).

Donley N, Jaruga P, Coskun E, Dizdaroglu M, McCullough AK, Lloyd RS. Donley N, et al. Among authors: coskun e. ACS Chem Biol. 2015 Oct 16;10(10):2334-43. doi: 10.1021/acschembio.5b00452. Epub 2015 Aug 7. ACS Chem Biol. 2015. PMID: 26218629 Free PMC article.

5

Extreme Expression of DNA Repair Protein Apurinic/Apyrimidinic Endonuclease 1 (APE1) in Human Breast Cancer As Measured by Liquid Chromatography and Isotope Dilution Tandem Mass Spectrometry.

Coskun E, Jaruga P, Reddy PT, Dizdaroglu M. Coskun E, et al. Biochemistry. 2015 Sep 29;54(38):5787-90. doi: 10.1021/acs.biochem.5b00928. Epub 2015 Sep 15. Biochemistry. 2015. PMID: 26359670

6

Repair of oxidatively induced DNA damage by DNA glycosylases: Mechanisms of action, substrate specificities and excision kinetics.

Dizdaroglu M, Coskun E, Jaruga P. Dizdaroglu M, et al. Among authors: coskun e. Mutat Res Rev Mutat Res. 2017 Jan-Mar;771:99-127. doi: 10.1016/j.mrrev.2017.02.001. Epub 2017 Feb 16. Mutat Res Rev Mutat Res. 2017. PMID: 28342455 Free PMC article. Review.

7

Inhibition by Tetrahydroquinoline Sulfonamide Derivatives of the Activity of Human 8-Oxoguanine DNA Glycosylase (OGG1) for Several Products of Oxidatively induced DNA Base Lesions.

Kant M, Tahara YK, Jaruga P, Coskun E, Lloyd RS, Kool ET, Dizdaroglu M. Kant M, et al. Among authors: coskun e. ACS Chem Biol. 2021 Jan 15;16(1):45-51. doi: 10.1021/acschembio.0c00877. Epub 2020 Dec 17. ACS Chem Biol. 2021. PMID: 33331782 Free PMC article.

8

DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model.

Paluri SL, Burak M, Senejani AG, Levinson M, Rahim T, Clairmont K, Kashgarian M, Alvarado-Cruz I, Meas R, Cardó-Vila M, Zeiss C, Maher S, Bothwell ALM, Coskun E, Kant M, Jaruga P, Dizdaroglu M, Stephen Lloyd R, Sweasy JB. Paluri SL, et al. Among authors: coskun e. DNA Repair (Amst). 2021 Sep;105:103152. doi: 10.1016/j.dnarep.2021.103152. Epub 2021 Jun 24. DNA Repair (Amst). 2021. PMID: 34186496 Free PMC article.

9

Bisphenol a promotes cell survival following oxidative DNA damage in mouse fibroblasts.

Gassman NR, Coskun E, Stefanick DF, Horton JK, Jaruga P, Dizdaroglu M, Wilson SH. Gassman NR, et al. Among authors: coskun e. PLoS One. 2015 Feb 18;10(2):e0118819. doi: 10.1371/journal.pone.0118819. eCollection 2015. PLoS One. 2015. PMID: 25693136 Free PMC article.

10

Production, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements.

Reddy PT, Jaruga P, Nelson BC, Lowenthal MS, Jemth AS, Loseva O, Coskun E, Helleday T, Dizdaroglu M. Reddy PT, et al. Among authors: coskun e. Methods Enzymol. 2016;566:305-32. doi: 10.1016/bs.mie.2015.06.044. Epub 2015 Jul 26. Methods Enzymol. 2016. PMID: 26791985 Free PMC article.

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