Young LS - Search Results

1

FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues.

Font-Tello A, Kesten N, Xie Y, Taing L, Varešlija D, Young LS, Hamid AA, Van Allen EM, Sweeney CJ, Gjini E, Lako A, Hodi FS, Bellmunt J, Brown M, Cejas P, Long HW. Font-Tello A, et al. Among authors: young ls. Nat Protoc. 2020 Aug;15(8):2503-2518. doi: 10.1038/s41596-020-0340-6. Epub 2020 Jun 26. Nat Protoc. 2020. PMID: 32591768

2

AIB1:ERα transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells.

O'Hara J, Vareslija D, McBryan J, Bane F, Tibbitts P, Byrne C, Conroy RM, Hao Y, Gaora PÓ, Hill AD, McIlroy M, Young LS. O'Hara J, et al. Among authors: young ls. Clin Cancer Res. 2012 Jun 15;18(12):3305-15. doi: 10.1158/1078-0432.CCR-11-3300. Epub 2012 May 1. Clin Cancer Res. 2012. PMID: 22550166

3

Transcriptomic Profiling of Sequential Tumors from Breast Cancer Patients Provides a Global View of Metastatic Expression Changes Following Endocrine Therapy.

McBryan J, Fagan A, McCartan D, Bane FT, Varešlija D, Cocchiglia S, Byrne C, Bolger J, McIlroy M, Hudson L, Tibbitts P, Gaora PÓ, Hill AD, Young LS. McBryan J, et al. Among authors: young ls. Clin Cancer Res. 2015 Dec 1;21(23):5371-9. doi: 10.1158/1078-0432.CCR-14-2155. Epub 2015 Aug 3. Clin Cancer Res. 2015. PMID: 26240272

4

Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors.

Varešlija D, McBryan J, Fagan A, Redmond AM, Hao Y, Sims AH, Turnbull A, Dixon JM, Ó Gaora P, Hudson L, Purcell S, Hill AD, Young LS. Varešlija D, et al. Among authors: young ls. Clin Cancer Res. 2016 Jun 1;22(11):2765-77. doi: 10.1158/1078-0432.CCR-15-1583. Epub 2016 Jan 13. Clin Cancer Res. 2016. PMID: 26763249 Free article.

5

Patient-Derived Xenografts of Breast Cancer.

Varešlija D, Cocchiglia S, Byrne C, Young L. Varešlija D, et al. Methods Mol Biol. 2017;1501:327-336. doi: 10.1007/978-1-4939-6475-8_17. Methods Mol Biol. 2017. PMID: 27796962

6

Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer.

Browne AL, Charmsaz S, Varešlija D, Fagan A, Cosgrove N, Cocchiglia S, Purcell S, Ward E, Bane F, Hudson L, Hill AD, Carroll JS, Redmond AM, Young LS. Browne AL, et al. Among authors: young ls. Oncogene. 2018 Apr;37(15):2008-2021. doi: 10.1038/s41388-017-0042-x. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367763 Free PMC article.

7

Epigenome-wide SRC-1-Mediated Gene Silencing Represses Cellular Differentiation in Advanced Breast Cancer.

Ward E, Varešlija D, Charmsaz S, Fagan A, Browne AL, Cosgrove N, Cocchiglia S, Purcell SP, Hudson L, Das S, O'Connor D, O'Halloran PJ, Sims AH, Hill AD, Young LS. Ward E, et al. Among authors: young ls. Clin Cancer Res. 2018 Aug 1;24(15):3692-3703. doi: 10.1158/1078-0432.CCR-17-2615. Epub 2018 Mar 22. Clin Cancer Res. 2018. PMID: 29567811

8

Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers.

Lindner AU, Lucantoni F, Varešlija D, Resler A, Murphy BM, Gallagher WM, Hill ADK, Young LS, Prehn JHM. Lindner AU, et al. Among authors: young ls. J Mol Med (Berl). 2018 Oct;96(10):1025-1037. doi: 10.1007/s00109-018-1675-0. Epub 2018 Aug 1. J Mol Med (Berl). 2018. PMID: 30069746

9

Altered Steroid Milieu in AI-Resistant Breast Cancer Facilitates AR Mediated Gene-Expression Associated with Poor Response to Therapy.

Creevey L, Bleach R, Madden SF, Toomey S, Bane FT, Varešlija D, Hill AD, Young LS, McIlroy M. Creevey L, et al. Among authors: young ls. Mol Cancer Ther. 2019 Oct;18(10):1731-1743. doi: 10.1158/1535-7163.MCT-18-0791. Epub 2019 Jul 9. Mol Cancer Ther. 2019. PMID: 31289138

10

A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival.

Giannoudis A, Clarke K, Zakaria R, Varešlija D, Farahani M, Rainbow L, Platt-Higgins A, Ruthven S, Brougham KA, Rudland PS, Jenkinson MD, Young LS, Falciani F, Palmieri C. Giannoudis A, et al. Among authors: young ls. Sci Rep. 2019 Dec 6;9(1):18518. doi: 10.1038/s41598-019-55084-z. Sci Rep. 2019. PMID: 31811234 Free PMC article.

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