Bahar I - Search Results

1

Identifying persistent structures in multiscale 'omics data.

Zheng F, Zhang S, Churas C, Pratt D, Bahar I, Ideker T. Zheng F, et al. Among authors: bahar i. bioRxiv [Preprint]. 2020 Oct 3:2020.06.16.151555. doi: 10.1101/2020.06.16.151555. bioRxiv. 2020. Update in: Genome Biol. 2021 Jan 7;22(1):21. doi: 10.1186/s13059-020-02228-4 PMID: 32587977 Free PMC article. Updated. Preprint.

2

Structure-Encoded Global Motions and Their Role in Mediating Protein-Substrate Interactions.

Bahar I, Cheng MH, Lee JY, Kaya C, Zhang S. Bahar I, et al. Biophys J. 2015 Sep 15;109(6):1101-9. doi: 10.1016/j.bpj.2015.06.004. Epub 2015 Jul 2. Biophys J. 2015. PMID: 26143655 Free PMC article. Review.

3

Chromosomal dynamics predicted by an elastic network model explains genome-wide accessibility and long-range couplings.

Sauerwald N, Zhang S, Kingsford C, Bahar I. Sauerwald N, et al. Among authors: bahar i. Nucleic Acids Res. 2017 Apr 20;45(7):3663-3673. doi: 10.1093/nar/gkx172. Nucleic Acids Res. 2017. PMID: 28334818 Free PMC article.

4

Shared dynamics of LeuT superfamily members and allosteric differentiation by structural irregularities and multimerization.

Ponzoni L, Zhang S, Cheng MH, Bahar I. Ponzoni L, et al. Among authors: bahar i. Philos Trans R Soc Lond B Biol Sci. 2018 Jun 19;373(1749):20170177. doi: 10.1098/rstb.2017.0177. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29735731 Free PMC article.

5

Shared Signature Dynamics Tempered by Local Fluctuations Enables Fold Adaptability and Specificity.

Zhang S, Li H, Krieger JM, Bahar I. Zhang S, et al. Among authors: bahar i. Mol Biol Evol. 2019 Sep 1;36(9):2053-2068. doi: 10.1093/molbev/msz102. Mol Biol Evol. 2019. PMID: 31028708 Free PMC article.

6

Trimerization of dopamine transporter triggered by AIM-100 binding: Molecular mechanism and effect of mutations.

Cheng MH, Ponzoni L, Sorkina T, Lee JY, Zhang S, Sorkin A, Bahar I. Cheng MH, et al. Among authors: bahar i. Neuropharmacology. 2019 Dec 15;161:107676. doi: 10.1016/j.neuropharm.2019.107676. Epub 2019 Jun 20. Neuropharmacology. 2019. PMID: 31228486 Free PMC article.

7

Intrinsic dynamics is evolutionarily optimized to enable allosteric behavior.

Zhang Y, Doruker P, Kaynak B, Zhang S, Krieger J, Li H, Bahar I. Zhang Y, et al. Among authors: bahar i. Curr Opin Struct Biol. 2020 Jun;62:14-21. doi: 10.1016/j.sbi.2019.11.002. Epub 2019 Nov 27. Curr Opin Struct Biol. 2020. PMID: 31785465 Free PMC article. Review.

8

Differences in the intrinsic spatial dynamics of the chromatin contribute to cell differentiation.

Zhang S, Chen F, Bahar I. Zhang S, et al. Among authors: bahar i. Nucleic Acids Res. 2020 Feb 20;48(3):1131-1145. doi: 10.1093/nar/gkz1102. Nucleic Acids Res. 2020. PMID: 31828312 Free PMC article.

9

An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations.

Cheng MH, Zhang S, Porritt RA, Arditi M, Bahar I. Cheng MH, et al. Among authors: bahar i. bioRxiv [Preprint]. 2020 May 21:2020.05.21.109272. doi: 10.1101/2020.05.21.109272. bioRxiv. 2020. Update in: Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25254-25262. doi: 10.1073/pnas.2010722117 PMID: 32511374 Free PMC article. Updated. Preprint.

10

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation.

Cheng MH, Zhang S, Porritt RA, Noval Rivas M, Paschold L, Willscher E, Binder M, Arditi M, Bahar I. Cheng MH, et al. Among authors: bahar i. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25254-25262. doi: 10.1073/pnas.2010722117. Epub 2020 Sep 28. Proc Natl Acad Sci U S A. 2020. PMID: 32989130 Free PMC article.

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