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Page 1
Circadian asthma airway responses are gated by REV-ERBα.
Durrington HJ, Krakowiak K, Meijer P, Begley N, Maidstone R, Goosey L, Gibbs JE, Blaikley JF, Gregory LG, Lloyd CM, Loudon ASI, Ray DW. Durrington HJ, et al. Among authors: maidstone r. Eur Respir J. 2020 Dec 17;56(6):1902407. doi: 10.1183/13993003.02407-2019. Print 2020 Dec. Eur Respir J. 2020. PMID: 32586876 Free PMC article.
REVERBa couples the circadian clock to hepatic glucocorticoid action.
Caratti G, Iqbal M, Hunter L, Kim D, Wang P, Vonslow RM, Begley N, Tetley AJ, Woodburn JL, Pariollaud M, Maidstone R, Donaldson IJ, Zhang Z, Ince LM, Kitchen G, Baxter M, Poolman TM, Daniels DA, Stirling DR, Brocker C, Gonzalez F, Loudon AS, Bechtold DA, Rattray M, Matthews LC, Ray DW. Caratti G, et al. Among authors: maidstone r. J Clin Invest. 2018 Oct 1;128(10):4454-4471. doi: 10.1172/JCI96138. Epub 2018 Sep 4. J Clin Invest. 2018. PMID: 30179226 Free PMC article.
Cough rhythms in asthma: Potential implication for management.
Lodhi S, Smith JA, Satia I, Holt KJ, Maidstone RJ, Durrington HJ. Lodhi S, et al. J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):2024-2027. doi: 10.1016/j.jaip.2018.12.020. Epub 2019 Jan 3. J Allergy Clin Immunol Pract. 2019. PMID: 30610923 Free PMC article. No abstract available.
Rheumatoid arthritis reprograms circadian output pathways.
Poolman TM, Gibbs J, Walker AL, Dickson S, Farrell L, Hensman J, Kendall AC, Maidstone R, Warwood S, Loudon A, Rattray M, Bruce IN, Nicolaou A, Ray DW. Poolman TM, et al. Among authors: maidstone r. Arthritis Res Ther. 2019 Feb 6;21(1):47. doi: 10.1186/s13075-019-1825-y. Arthritis Res Ther. 2019. PMID: 30728072 Free PMC article.
Genome-wide effect of pulmonary airway epithelial cell-specific Bmal1 deletion.
Zhang Z, Hunter L, Wu G, Maidstone R, Mizoro Y, Vonslow R, Fife M, Hopwood T, Begley N, Saer B, Wang P, Cunningham P, Baxter M, Durrington H, Blaikley JF, Hussell T, Rattray M, Hogenesch JB, Gibbs J, Ray DW, Loudon ASI. Zhang Z, et al. Among authors: maidstone r. FASEB J. 2019 May;33(5):6226-6238. doi: 10.1096/fj.201801682R. Epub 2019 Feb 22. FASEB J. 2019. PMID: 30794439 Free PMC article.
Thus, the local circadian clock in AECs is vital in lung health by coordinating major cell processes such as metabolism and immunity.-Zhang, Z. Hunter, L., Wu, G., Maidstone, R., Mizoro, Y., Vonslow, R., Fife, M., Hopwood, T., Begley, N., Saer, B., Wang, P., …
Thus, the local circadian clock in AECs is vital in lung health by coordinating major cell processes such as metabolism and immunity.-Zhang, …
Circadian rhythm of exhaled biomarkers in health and asthma.
Wilkinson M, Maidstone R, Loudon A, Blaikley J, White IR, Singh D, Ray DW, Goodacre R, Fowler SJ, Durrington HJ. Wilkinson M, et al. Among authors: maidstone r. Eur Respir J. 2019 Oct 17;54(4):1901068. doi: 10.1183/13993003.01068-2019. Print 2019 Oct. Eur Respir J. 2019. PMID: 31221808 Free PMC article.
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.
Kitchen GB, Cunningham PS, Poolman TM, Iqbal M, Maidstone R, Baxter M, Bagnall J, Begley N, Saer B, Hussell T, Matthews LC, Dockrell DH, Durrington HJ, Gibbs JE, Blaikley JF, Loudon AS, Ray DW. Kitchen GB, et al. Among authors: maidstone r. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1543-1551. doi: 10.1073/pnas.1915932117. Epub 2020 Jan 3. Proc Natl Acad Sci U S A. 2020. PMID: 31900362 Free PMC article.
25 results