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A New Potent and Selective Monoamine Oxidase-B Inhibitor with Extended Conjugation in a Chalcone Framework: 1-[4-(Morpholin-4-yl)phenyl]-5-phenylpenta-2,4-dien-1-one.
Maliyakkal N, Eom BH, Heo JH, Abdullah Almoyad MA, Thomas Parambi DG, Gambacorta N, Nicolotti O, Beeran AA, Kim H, Mathew B. Maliyakkal N, et al. Among authors: thomas parambi dg. ChemMedChem. 2020 Sep 3;15(17):1629-1633. doi: 10.1002/cmdc.202000305. Epub 2020 Jul 15. ChemMedChem. 2020. PMID: 32583952
Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study.
Thomas Parambi DG, Oh JM, Kumar S, Sudevan ST, Hendawy OM, Abdelgawad MA, Musa A, Al-Sanea MM, Ahmad I, Patel H, Kim H, Mathew B. Thomas Parambi DG, et al. Comput Biol Chem. 2023 Aug;105:107899. doi: 10.1016/j.compbiolchem.2023.107899. Epub 2023 Jun 1. Comput Biol Chem. 2023. PMID: 37315342