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Nitration of tau protein is linked to neurodegeneration in tauopathies.
Horiguchi T, Uryu K, Giasson BI, Ischiropoulos H, LightFoot R, Bellmann C, Richter-Landsberg C, Lee VM, Trojanowski JQ. Horiguchi T, et al. Among authors: giasson bi. Am J Pathol. 2003 Sep;163(3):1021-31. doi: 10.1016/S0002-9440(10)63462-1. Am J Pathol. 2003. PMID: 12937143 Free PMC article.
Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy.
Clippinger AK, D'Alton S, Lin WL, Gendron TF, Howard J, Borchelt DR, Cannon A, Carlomagno Y, Chakrabarty P, Cook C, Golde TE, Levites Y, Ranum L, Schultheis PJ, Xu G, Petrucelli L, Sahara N, Dickson DW, Giasson B, Lewis J. Clippinger AK, et al. Acta Neuropathol. 2013 Jul;126(1):39-50. doi: 10.1007/s00401-013-1123-8. Epub 2013 May 11. Acta Neuropathol. 2013. PMID: 23666556 Free PMC article.
LRRK2 phosphorylates novel tau epitopes and promotes tauopathy.
Bailey RM, Covy JP, Melrose HL, Rousseau L, Watkinson R, Knight J, Miles S, Farrer MJ, Dickson DW, Giasson BI, Lewis J. Bailey RM, et al. Among authors: giasson bi. Acta Neuropathol. 2013 Dec;126(6):809-27. doi: 10.1007/s00401-013-1188-4. Epub 2013 Oct 11. Acta Neuropathol. 2013. PMID: 24113872 Free PMC article.
Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission.
Chakrabarty P, Hudson VJ III, Sacino AN, Brooks MM, D'Alton S, Lewis J, Golde TE, Giasson BI. Chakrabarty P, et al. Among authors: giasson bi. Acta Neuropathol. 2015 Aug;130(2):303-5. doi: 10.1007/s00401-015-1444-x. Epub 2015 May 16. Acta Neuropathol. 2015. PMID: 25982997 Free PMC article. No abstract available.
Non-prion-type transmission in A53T α-synuclein transgenic mice: a normal component of spinal homogenates from naïve non-transgenic mice induces robust α-synuclein pathology.
Sacino AN, Ayers JI, Brooks MM, Chakrabarty P, Hudson VJ 3rd, Howard JK, Golde TE, Giasson BI, Borchelt DR. Sacino AN, et al. Among authors: giasson bi. Acta Neuropathol. 2016 Jan;131(1):151-4. doi: 10.1007/s00401-015-1505-1. Epub 2015 Nov 5. Acta Neuropathol. 2016. PMID: 26541429 Free PMC article. No abstract available.
216 results