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The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels.
Zhou Y, Cai S, Moutal A, Yu J, Gómez K, Madura CL, Shan Z, Pham NYN, Serafini MJ, Dorame A, Scott DD, François-Moutal L, Perez-Miller S, Patek M, Khanna M, Khanna R. Zhou Y, et al. Among authors: gomez k. ACS Chem Neurosci. 2019 Dec 18;10(12):4834-4846. doi: 10.1021/acschemneuro.9b00547. Epub 2019 Nov 21. ACS Chem Neurosci. 2019. PMID: 31697467
1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain.
Zhou Y, Cai S, Gomez K, Wijeratne EMK, Ji Y, Bellampalli SS, Luo S, Moutal A, Gunatilaka AAL, Khanna R. Zhou Y, et al. Among authors: gomez k. Mol Brain. 2020 May 11;13(1):73. doi: 10.1186/s13041-020-00616-2. Mol Brain. 2020. PMID: 32393368 Free PMC article.
A modulator of the low-voltage-activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies.
Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Yen Ngan Pham N, Molnar G, Streicher JM, Patek M, Perez-Miller S, Moutal A, Wang J, Khanna R. Cai S, et al. Among authors: gomez k. Pain. 2020 Nov;161(11):2551-2570. doi: 10.1097/j.pain.0000000000001955. Pain. 2020. PMID: 32541387 Free PMC article.
Putative roles of SLC7A5 (LAT1) transporter in pain.
Alles SRA, Gomez K, Moutal A, Khanna R. Alles SRA, et al. Among authors: gomez k. Neurobiol Pain. 2020 Jun 30;8:100050. doi: 10.1016/j.ynpai.2020.100050. eCollection 2020 Aug-Dec. Neurobiol Pain. 2020. PMID: 32715162 Free PMC article. Review.
The role of cyclin-dependent kinase 5 in neuropathic pain.
Gomez K, Vallecillo TGM, Moutal A, Perez-Miller S, Delgado-Lezama R, Felix R, Khanna R. Gomez K, et al. Pain. 2020 Dec;161(12):2674-2689. doi: 10.1097/j.pain.0000000000002027. Pain. 2020. PMID: 32773603 Free PMC article. Review.
SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia.
Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R. Moutal A, et al. Among authors: gomez k. bioRxiv [Preprint]. 2020 Sep 14:2020.07.17.209288. doi: 10.1101/2020.07.17.209288. bioRxiv. 2020. Update in: Pain. 2021 Jan;162(1):243-252. doi: 10.1097/j.pain.0000000000002097 PMID: 32869019 Free PMC article. Updated. Preprint.
Targeting T-type/CaV3.2 channels for chronic pain.
Cai S, Gomez K, Moutal A, Khanna R. Cai S, et al. Among authors: gomez k. Transl Res. 2021 Aug;234:20-30. doi: 10.1016/j.trsl.2021.01.002. Epub 2021 Jan 7. Transl Res. 2021. PMID: 33422652 Free PMC article. Review.
372 results