Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

166 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer.
Escobar-Hoyos LF, Penson A, Kannan R, Cho H, Pan CH, Singh RK, Apken LH, Hobbs GA, Luo R, Lecomte N, Babu S, Pan FC, Alonso-Curbelo D, Morris JP 4th, Askan G, Grbovic-Huezo O, Ogrodowski P, Bermeo J, Saglimbeni J, Cruz CD, Ho YJ, Lawrence SA, Melchor JP, Goda GA, Bai K, Pastore A, Hogg SJ, Raghavan S, Bailey P, Chang DK, Biankin A, Shroyer KR, Wolpin BM, Aguirre AJ, Ventura A, Taylor B, Der CJ, Dominguez D, Kümmel D, Oeckinghaus A, Lowe SW, Bradley RK, Abdel-Wahab O, Leach SD. Escobar-Hoyos LF, et al. Among authors: leach sd. Cancer Cell. 2020 Aug 10;38(2):198-211.e8. doi: 10.1016/j.ccell.2020.05.010. Epub 2020 Jun 18. Cancer Cell. 2020. PMID: 32559497 Free PMC article.
PanIN Neuroendocrine Cells Promote Tumorigenesis via Neuronal Cross-talk.
Sinha S, Fu YY, Grimont A, Ketcham M, Lafaro K, Saglimbeni JA, Askan G, Bailey JM, Melchor JP, Zhong Y, Joo MG, Grbovic-Huezo O, Yang IH, Basturk O, Baker L, Park Y, Kurtz RC, Tuveson D, Leach SD, Pasricha PJ. Sinha S, et al. Among authors: leach sd. Cancer Res. 2017 Apr 15;77(8):1868-1879. doi: 10.1158/0008-5472.CAN-16-0899-T. Epub 2017 Apr 6. Cancer Res. 2017. PMID: 28386018 Free PMC article.
Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma.
Grbovic-Huezo O, Pitter KL, Lecomte N, Saglimbeni J, Askan G, Holm M, Melchor JP, Chandwani R, Joshi S, Haglund C, Iacobuzio-Donahue CA, Chiosis G, Tammela T, Leach SD. Grbovic-Huezo O, et al. Among authors: leach sd. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30670-30678. doi: 10.1073/pnas.1920240117. Epub 2020 Nov 16. Proc Natl Acad Sci U S A. 2020. PMID: 33199632 Free PMC article.
Ordered and deterministic cancer genome evolution after p53 loss.
Baslan T, Morris JP 4th, Zhao Z, Reyes J, Ho YJ, Tsanov KM, Bermeo J, Tian S, Zhang S, Askan G, Yavas A, Lecomte N, Erakky A, Varghese AM, Zhang A, Kendall J, Ghiban E, Chorbadjiev L, Wu J, Dimitrova N, Chadalavada K, Nanjangud GJ, Bandlamudi C, Gong Y, Donoghue MTA, Socci ND, Krasnitz A, Notta F, Leach SD, Iacobuzio-Donahue CA, Lowe SW. Baslan T, et al. Among authors: leach sd. Nature. 2022 Aug;608(7924):795-802. doi: 10.1038/s41586-022-05082-5. Epub 2022 Aug 17. Nature. 2022. PMID: 35978189 Free PMC article.
Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules.
Singh K, Lin J, Lecomte N, Mohan P, Gokce A, Sanghvi VR, Jiang M, Grbovic-Huezo O, Burčul A, Stark SG, Romesser PB, Chang Q, Melchor JP, Beyer RK, Duggan M, Fukase Y, Yang G, Ouerfelli O, Viale A, de Stanchina E, Stamford AW, Meinke PT, Rätsch G, Leach SD, Ouyang Z, Wendel HG. Singh K, et al. Among authors: leach sd. Cancer Res. 2021 Apr 15;81(8):2002-2014. doi: 10.1158/0008-5472.CAN-20-2929. Epub 2021 Feb 25. Cancer Res. 2021. PMID: 33632898 Free PMC article.
α-Ketoglutarate links p53 to cell fate during tumour suppression.
Morris JP 4th, Yashinskie JJ, Koche R, Chandwani R, Tian S, Chen CC, Baslan T, Marinkovic ZS, Sánchez-Rivera FJ, Leach SD, Carmona-Fontaine C, Thompson CB, Finley LWS, Lowe SW. Morris JP 4th, et al. Among authors: leach sd. Nature. 2019 Sep;573(7775):595-599. doi: 10.1038/s41586-019-1577-5. Epub 2019 Sep 18. Nature. 2019. PMID: 31534224 Free PMC article.
ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer.
Huang YH, Hu J, Chen F, Lecomte N, Basnet H, David CJ, Witkin MD, Allen PJ, Leach SD, Hollmann TJ, Iacobuzio-Donahue CA, Massagué J. Huang YH, et al. Among authors: leach sd. Cancer Discov. 2020 Jan;10(1):142-157. doi: 10.1158/2159-8290.CD-19-0529. Epub 2019 Oct 3. Cancer Discov. 2020. PMID: 31582374 Free PMC article.
A gene-environment-induced epigenetic program initiates tumorigenesis.
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan W, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe'er D, Lowe SW. Alonso-Curbelo D, et al. Among authors: leach sd. Nature. 2021 Feb;590(7847):642-648. doi: 10.1038/s41586-020-03147-x. Epub 2021 Feb 3. Nature. 2021. PMID: 33536616 Free PMC article.
166 results