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Cerebrospinal fluid hemoglobin drives subarachnoid hemorrhage-related secondary brain injury.
Akeret K, Buzzi RM, Schaer CA, Thomson BR, Vallelian F, Wang S, Willms J, Sebök M, Held U, Deuel JW, Humar R, Regli L, Keller E, Hugelshofer M, Schaer DJ. Akeret K, et al. Among authors: schaer ca. J Cereb Blood Flow Metab. 2021 Nov;41(11):3000-3015. doi: 10.1177/0271678X211020629. Epub 2021 Jun 8. J Cereb Blood Flow Metab. 2021. PMID: 34102922 Free PMC article.
Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia.
Vallelian F, Buzzi RM, Pfefferlé M, Yalamanoglu A, Dubach IL, Wassmer A, Gentinetta T, Hansen K, Humar R, Schulthess N, Schaer CA, Schaer DJ. Vallelian F, et al. Among authors: schaer ca. Cell Death Differ. 2022 Aug;29(8):1450-1465. doi: 10.1038/s41418-022-00932-1. Epub 2022 Jan 14. Cell Death Differ. 2022. PMID: 35031770 Free PMC article.
Revisiting the putative role of heme as a trigger of inflammation.
Vallelian F, Schaer CA, Deuel JW, Ingoglia G, Humar R, Buehler PW, Schaer DJ. Vallelian F, et al. Among authors: schaer dj, schaer ca. Pharmacol Res Perspect. 2018 Mar 30;6(2):e00392. doi: 10.1002/prp2.392. eCollection 2018 Apr. Pharmacol Res Perspect. 2018. PMID: 29610666 Free PMC article.
Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes.
Pfefferlé M, Ingoglia G, Schaer CA, Yalamanoglu A, Buzzi R, Dubach IL, Tan G, López-Cano EY, Schulthess N, Hansen K, Humar R, Schaer DJ, Vallelian F. Pfefferlé M, et al. Among authors: schaer ca. J Clin Invest. 2020 Oct 1;130(10):5576-5590. doi: 10.1172/JCI137282. J Clin Invest. 2020. PMID: 32663195 Free PMC article.
27 results