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CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ. Lowey B, et al. Among authors: mekalanos jj. Cell. 2020 Jul 9;182(1):38-49.e17. doi: 10.1016/j.cell.2020.05.019. Epub 2020 Jun 15. Cell. 2020. PMID: 32544385 Free PMC article.
Cyclic dinucleotides and the innate immune response.
Danilchanka O, Mekalanos JJ. Danilchanka O, et al. Among authors: mekalanos jj. Cell. 2013 Aug 29;154(5):962-970. doi: 10.1016/j.cell.2013.08.014. Cell. 2013. PMID: 23993090 Free PMC article. Review.
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ, Kranzusch PJ. Whiteley AT, et al. Among authors: mekalanos jj. Nature. 2019 Mar;567(7747):194-199. doi: 10.1038/s41586-019-0953-5. Epub 2019 Feb 20. Nature. 2019. PMID: 30787435 Free PMC article.
Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD. Lau RK, et al. Among authors: mekalanos jj. Mol Cell. 2020 Feb 20;77(4):723-733.e6. doi: 10.1016/j.molcel.2019.12.010. Epub 2020 Jan 10. Mol Cell. 2020. PMID: 31932164 Free PMC article.
Bacterial genomics and pathogen evolution.
Raskin DM, Seshadri R, Pukatzki SU, Mekalanos JJ. Raskin DM, et al. Among authors: mekalanos jj. Cell. 2006 Feb 24;124(4):703-14. doi: 10.1016/j.cell.2006.02.002. Cell. 2006. PMID: 16497582 Free article. Review.
311 results