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Vascular origin of vildagliptin-induced skin effects in Cynomolgus monkeys: pathomechanistic role of peripheral sympathetic system and neuropeptide Y.
Hoffmann P, Bentley P, Sahota P, Schoenfeld H, Martin L, Longo L, Spaet R, Moulin P, Pantano S, Dubost V, Lapadula D, Burkey B, Kaushik V, Zhou W, Hayes M, Flavahan N, Chibout SD, Busch S. Hoffmann P, et al. Among authors: lapadula d. Toxicol Pathol. 2014 Jun;42(4):684-95. doi: 10.1177/0192623313516828. Epub 2014 Jan 20. Toxicol Pathol. 2014. PMID: 24448599
Acute Toxicity of Vildagliptin.
Hoffmann P, Martin L, Keselica M, Gunson D, Skuba E, Lapadula D, Hayes M, Bentley P, Busch S. Hoffmann P, et al. Among authors: lapadula d. Toxicol Pathol. 2017 Jan;45(1):76-83. doi: 10.1177/0192623316672944. Epub 2016 Oct 17. Toxicol Pathol. 2017. PMID: 27753637
ICH guidelines: inception, revision, and implications for drug development.
Wang T, Jacobson-Kram D, Pilaro AM, Lapadula D, Jacobs A, Brown P, Lipscomb J, McGuinn WD. Wang T, et al. Among authors: lapadula d. Toxicol Sci. 2010 Dec;118(2):356-67. doi: 10.1093/toxsci/kfq286. Epub 2010 Sep 22. Toxicol Sci. 2010. PMID: 20861066 No abstract available.
Targeting Oncogenic Gαq/11 in Uveal Melanoma.
Lapadula D, Benovic JL. Lapadula D, et al. Cancers (Basel). 2021 Dec 9;13(24):6195. doi: 10.3390/cancers13246195. Cancers (Basel). 2021. PMID: 34944815 Free PMC article. Review.
Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma.
Lapadula D, Farias E, Randolph CE, Purwin TJ, McGrath D, Charpentier TH, Zhang L, Wu S, Terai M, Sato T, Tall GG, Zhou N, Wedegaertner PB, Aplin AE, Aguirre-Ghiso J, Benovic JL. Lapadula D, et al. Mol Cancer Res. 2019 Apr;17(4):963-973. doi: 10.1158/1541-7786.MCR-18-0574. Epub 2018 Dec 19. Mol Cancer Res. 2019. PMID: 30567972 Free PMC article.
A tissue-specific enhancer of the C. elegans nhr-67/tailless gene drives coordinated expression in uterine stem cells and the differentiated anchor cell.
Bodofsky S, Liberatore K, Pioppo L, Lapadula D, Thompson L, Birnbaum S, McClung G, Kartik A, Clever S, Wightman B. Bodofsky S, et al. Among authors: lapadula d. Gene Expr Patterns. 2018 Dec;30:71-81. doi: 10.1016/j.gep.2018.10.003. Epub 2018 Nov 4. Gene Expr Patterns. 2018. PMID: 30404043 Free PMC article.
52 results