Byrne L - Search Results

1

Pharmacological clearance of misfolded rhodopsin for the treatment of RHO-associated retinitis pigmentosa.

Liu X, Feng B, Vats A, Tang H, Seibel W, Swaroop M, Tawa G, Zheng W, Byrne L, Schurdak M, Chen Y. Liu X, et al. Among authors: byrne l. FASEB J. 2020 Aug;34(8):10146-10167. doi: 10.1096/fj.202000282R. Epub 2020 Jun 14. FASEB J. 2020. PMID: 32536017 Free PMC article.

2

Gene augmentation prevents retinal degeneration in a CRISPR/Cas9-based mouse model of PRPF31 retinitis pigmentosa.

Xi Z, Vats A, Sahel JA, Chen Y, Byrne LC. Xi Z, et al. Nat Commun. 2022 Dec 13;13(1):7695. doi: 10.1038/s41467-022-35361-8. Nat Commun. 2022. PMID: 36509783 Free PMC article.

3

Retinal Explant Culture from Mouse, Human, and Nonhuman Primates and Its Applications in Vision Research.

Vats A, Xi Z, Byrne LC, Chen Y. Vats A, et al. Methods Mol Biol. 2025;2848:169-186. doi: 10.1007/978-1-0716-4087-6_11. Methods Mol Biol. 2025. PMID: 39240523

4

Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue.

Rodrigues A, Slembrouck-Brec A, Nanteau C, Terray A, Tymoshenko Y, Zagar Y, Reichman S, Xi Z, Sahel JA, Fouquet S, Orieux G, Nandrot EF, Byrne LC, Audo I, Roger JE, Goureau O. Rodrigues A, et al. NPJ Regen Med. 2022 Aug 16;7(1):39. doi: 10.1038/s41536-022-00235-6. NPJ Regen Med. 2022. PMID: 35974011 Free PMC article.

5

Anti-VEGF AAV2 injections: The fewer the better.

Byrne LC. Byrne LC. Sci Transl Med. 2017 Jun 7;9(393):eaan4921. doi: 10.1126/scitranslmed.aan4921. Sci Transl Med. 2017. PMID: 28592565

6

Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration.

Byrne LC, Dalkara D, Luna G, Fisher SK, Clérin E, Sahel JA, Léveillard T, Flannery JG. Byrne LC, et al. J Clin Invest. 2015 Jan;125(1):105-16. doi: 10.1172/JCI65654. Epub 2014 Nov 21. J Clin Invest. 2015. PMID: 25415434 Free PMC article.

7

Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis.

Aït-Ali N, Fridlich R, Millet-Puel G, Clérin E, Delalande F, Jaillard C, Blond F, Perrocheau L, Reichman S, Byrne LC, Olivier-Bandini A, Bellalou J, Moyse E, Bouillaud F, Nicol X, Dalkara D, van Dorsselaer A, Sahel JA, Léveillard T. Aït-Ali N, et al. Among authors: byrne lc. Cell. 2015 May 7;161(4):817-32. doi: 10.1016/j.cell.2015.03.023. Cell. 2015. PMID: 25957687 Free article.

8

Delivery of Genetic Information: Viral Vector and Nonviral Vector Gene Therapies.

Gemayel M, Byrne LC, Ciulla T, Sahel JA. Gemayel M, et al. Int Ophthalmol Clin. 2021 Jul 1;61(3):35-57. doi: 10.1097/IIO.0000000000000360. Int Ophthalmol Clin. 2021. PMID: 34196317 No abstract available.

9

scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution.

Öztürk BE, Johnson ME, Kleyman M, Turunç S, He J, Jabalameli S, Xi Z, Visel M, Dufour VL, Iwabe S, Pompeo Marinho LFL, Aguirre GD, Sahel JA, Schaffer DV, Pfenning AR, Flannery JG, Beltran WA, Stauffer WR, Byrne LC. Öztürk BE, et al. Among authors: byrne lc. Elife. 2021 Oct 19;10:e64175. doi: 10.7554/eLife.64175. Elife. 2021. PMID: 34664552 Free PMC article.

10

Quantitative single-cell transcriptome-based ranking of engineered AAVs in human retinal explants.

Xi Z, Öztürk BE, Johnson ME, Turunç S, Stauffer WR, Byrne LC. Xi Z, et al. Mol Ther Methods Clin Dev. 2022 Apr 30;25:476-489. doi: 10.1016/j.omtm.2022.04.014. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35615708 Free PMC article.

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