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An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer.
Pan CH, Otsuka Y, Sridharan B, Woo M, Leiton CV, Babu S, Torrente Gonçalves M, Kawalerski RR, K Bai JD, Chang DK, Biankin AV, Scampavia L, Spicer T, Escobar-Hoyos LF, Shroyer KR. Pan CH, et al. Among authors: scampavia l. Mol Oncol. 2020 Aug;14(8):1800-1816. doi: 10.1002/1878-0261.12743. Epub 2020 Jul 4. Mol Oncol. 2020. PMID: 32533886 Free PMC article.
Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening.
Pedró-Rosa L, Buckner FS, Ranade RM, Eberhart C, Madoux F, Gillespie JR, Koh CY, Brown S, Lohse J, Verlinde CL, Fan E, Bannister T, Scampavia L, Hol WG, Spicer T, Hodder P. Pedró-Rosa L, et al. Among authors: scampavia l. J Biomol Screen. 2015 Jan;20(1):122-30. doi: 10.1177/1087057114548832. Epub 2014 Aug 27. J Biomol Screen. 2015. PMID: 25163684 Free PMC article.
Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4).
Smith E, Chase P, Niswender CM, Utley TJ, Sheffler DJ, Noetzel MJ, Lamsal A, Wood MR, Conn PJ, Lindsley CW, Madoux F, Acosta M, Scampavia L, Spicer T, Hodder P. Smith E, et al. Among authors: scampavia l. J Biomol Screen. 2015 Aug;20(7):858-68. doi: 10.1177/1087057115581770. Epub 2015 Apr 15. J Biomol Screen. 2015. PMID: 25877150 Free PMC article.
104 results