Westaway D - Search Results

1

Metabolomic study of disease progression in scrapie prion infected mice; validation of a novel method for brain metabolite extraction.

Fu ZL, Mercier P, Eskandari-Sedighi G, Yang J, Westaway D, Sykes BD. Fu ZL, et al. Among authors: westaway d. Metabolomics. 2020 Jun 12;16(6):72. doi: 10.1007/s11306-020-01690-2. Metabolomics. 2020. PMID: 32533504

2

Biology of the prion gene complex.

Mastrangelo P, Westaway D. Mastrangelo P, et al. Among authors: westaway d. Biochem Cell Biol. 2001;79(5):613-28. doi: 10.1139/o01-142. Biochem Cell Biol. 2001. PMID: 11716303 Review.

3

Mouse models of Alzheimer's disease: the long and filamentous road.

Phinney AL, Horne P, Yang J, Janus C, Bergeron C, Westaway D. Phinney AL, et al. Among authors: westaway d. Neurol Res. 2003 Sep;25(6):590-600. doi: 10.1179/016164103101202020. Neurol Res. 2003. PMID: 14503012 Review.

4

The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections.

Watts JC, Drisaldi B, Ng V, Yang J, Strome B, Horne P, Sy MS, Yoong L, Young R, Mastrangelo P, Bergeron C, Fraser PE, Carlson GA, Mount HT, Schmitt-Ulms G, Westaway D. Watts JC, et al. Among authors: westaway d. EMBO J. 2007 Sep 5;26(17):4038-50. doi: 10.1038/sj.emboj.7601830. Epub 2007 Aug 16. EMBO J. 2007. PMID: 17703189 Free PMC article.

5

Actions of β-amyloid protein on human neurons are expressed through the amylin receptor.

Jhamandas JH, Li Z, Westaway D, Yang J, Jassar S, MacTavish D. Jhamandas JH, et al. Among authors: westaway d. Am J Pathol. 2011 Jan;178(1):140-9. doi: 10.1016/j.ajpath.2010.11.022. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224052 Free PMC article.

6

Aβ inhibition of ionic conductance in mouse basal forebrain neurons is dependent upon the cellular prion protein PrPC.

Alier K, Ma L, Yang J, Westaway D, Jhamandas JH. Alier K, et al. Among authors: westaway d. J Neurosci. 2011 Nov 9;31(45):16292-7. doi: 10.1523/JNEUROSCI.4367-11.2011. J Neurosci. 2011. PMID: 22072680 Free PMC article.

7

Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.

Westaway D, Genovesi S, Daude N, Brown R, Lau A, Lee I, Mays CE, Coomaraswamy J, Canine B, Pitstick R, Herbst A, Yang J, Ko KW, Schmitt-Ulms G, Dearmond SJ, McKenzie D, Hood L, Carlson GA. Westaway D, et al. PLoS Pathog. 2011 Nov;7(11):e1002391. doi: 10.1371/journal.ppat.1002391. Epub 2011 Nov 17. PLoS Pathog. 2011. PMID: 22114562 Free PMC article.

8

Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency.

Daude N, Wohlgemuth S, Brown R, Pitstick R, Gapeshina H, Yang J, Carlson GA, Westaway D. Daude N, et al. Among authors: westaway d. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9035-40. doi: 10.1073/pnas.1202130109. Epub 2012 May 22. Proc Natl Acad Sci U S A. 2012. PMID: 22619325 Free PMC article.

9

Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin.

Maulik M, Ghoshal B, Kim J, Wang Y, Yang J, Westaway D, Kar S. Maulik M, et al. Among authors: westaway d. Hum Mol Genet. 2012 Nov 15;21(22):4857-75. doi: 10.1093/hmg/dds322. Epub 2012 Aug 6. Hum Mol Genet. 2012. PMID: 22869680

10

The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6.

Mercer RC, Ma L, Watts JC, Strome R, Wohlgemuth S, Yang J, Cashman NR, Coulthart MB, Schmitt-Ulms G, Jhamandas JH, Westaway D. Mercer RC, et al. Among authors: westaway d. J Biol Chem. 2013 Dec 27;288(52):37241-55. doi: 10.1074/jbc.M113.488650. Epub 2013 Nov 13. J Biol Chem. 2013. PMID: 24225951 Free PMC article.

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