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A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
Pattwell SS, Arora S, Cimino PJ, Ozawa T, Szulzewsky F, Hoellerbauer P, Bonifert T, Hoffstrom BG, Boiani NE, Bolouri H, Correnti CE, Oldrini B, Silber JR, Squatrito M, Paddison PJ, Holland EC. Pattwell SS, et al. Among authors: ozawa t. Nat Commun. 2020 Jun 12;11(1):2977. doi: 10.1038/s41467-020-16786-5. Nat Commun. 2020. PMID: 32532995 Free PMC article.
Oncogenic role of a developmentally regulated NTRK2 splice variant.
Pattwell SS, Arora S, Nuechterlein N, Zager M, Loeb KR, Cimino PJ, Holland NC, Reche-Ley N, Bolouri H, Almiron Bonnin DA, Szulzewsky F, Phadnis VV, Ozawa T, Wagner MJ, Haffner MC, Cao J, Shendure J, Holland EC. Pattwell SS, et al. Among authors: ozawa t. Sci Adv. 2022 Oct 7;8(40):eabo6789. doi: 10.1126/sciadv.abo6789. Epub 2022 Oct 7. Sci Adv. 2022. PMID: 36206341 Free PMC article.
Rethinking glioma treatment strategy.
Ozawa T, Holland EC. Ozawa T, et al. Oncotarget. 2014 Oct 30;5(20):9532-3. doi: 10.18632/oncotarget.2619. Oncotarget. 2014. PMID: 25393981 Free PMC article. No abstract available.
Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.
Szulzewsky F, Arora S, Hoellerbauer P, King C, Nathan E, Chan M, Cimino PJ, Ozawa T, Kawauchi D, Pajtler KW, Gilbertson RJ, Paddison PJ, Vasioukhin V, Gujral TS, Holland EC. Szulzewsky F, et al. Among authors: ozawa t. Genes Dev. 2020 Aug 1;34(15-16):1051-1064. doi: 10.1101/gad.338681.120. Epub 2020 Jul 16. Genes Dev. 2020. PMID: 32675324 Free PMC article.
2,608 results