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A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
Pattwell SS, Arora S, Cimino PJ, Ozawa T, Szulzewsky F, Hoellerbauer P, Bonifert T, Hoffstrom BG, Boiani NE, Bolouri H, Correnti CE, Oldrini B, Silber JR, Squatrito M, Paddison PJ, Holland EC. Pattwell SS, et al. Among authors: bonifert t. Nat Commun. 2020 Jun 12;11(1):2977. doi: 10.1038/s41467-020-16786-5. Nat Commun. 2020. PMID: 32532995 Free PMC article.