Lu X - Search Results

1

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.

Louphrasitthiphol P, Siddaway R, Loffreda A, Pogenberg V, Friedrichsen H, Schepsky A, Zeng Z, Lu M, Strub T, Freter R, Lisle R, Suer E, Thomas B, Schuster-Böckler B, Filippakopoulos P, Middleton M, Lu X, Patton EE, Davidson I, Lambert JP, Wilmanns M, Steingrímsson E, Mazza D, Goding CR. Louphrasitthiphol P, et al. Among authors: lu x, lu m. Mol Cell. 2020 Aug 6;79(3):472-487.e10. doi: 10.1016/j.molcel.2020.05.025. Epub 2020 Jun 11. Mol Cell. 2020. PMID: 32531202 Free PMC article.

2

RB regulates the stability and the apoptotic function of p53 via MDM2.

Hsieh JK, Chan FS, O'Connor DJ, Mittnacht S, Zhong S, Lu X. Hsieh JK, et al. Among authors: lu x. Mol Cell. 1999 Feb;3(2):181-93. doi: 10.1016/s1097-2765(00)80309-3. Mol Cell. 1999. PMID: 10078201 Free article.

3

PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

Lapi E, Di Agostino S, Donzelli S, Gal H, Domany E, Rechavi G, Pandolfi PP, Givol D, Strano S, Lu X, Blandino G. Lapi E, et al. Among authors: lu x. Mol Cell. 2008 Dec 26;32(6):803-14. doi: 10.1016/j.molcel.2008.11.019. Mol Cell. 2008. PMID: 19111660 Free article.

4

Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification.

Notari M, Hu Y, Koch S, Lu M, Ratnayaka I, Zhong S, Baer C, Pagotto A, Goldin R, Salter V, Candi E, Melino G, Lu X. Notari M, et al. Among authors: lu x, lu m. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16645-50. doi: 10.1073/pnas.1102292108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2011. PMID: 21930934 Free PMC article.

5

Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif.

Llanos S, Royer C, Lu M, Bergamaschi D, Lee WH, Lu X. Llanos S, et al. Among authors: lu x, lu m. J Biol Chem. 2011 Dec 16;286(50):43039-44. doi: 10.1074/jbc.M111.270751. Epub 2011 Oct 13. J Biol Chem. 2011. PMID: 21998301 Free PMC article.

6

Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.

Lu M, Breyssens H, Salter V, Zhong S, Hu Y, Baer C, Ratnayaka I, Sullivan A, Brown NR, Endicott J, Knapp S, Kessler BM, Middleton MR, Siebold C, Jones EY, Sviderskaya EV, Cebon J, John T, Caballero OL, Goding CR, Lu X. Lu M, et al. Among authors: lu x. Cancer Cell. 2013 May 13;23(5):618-33. doi: 10.1016/j.ccr.2013.03.013. Epub 2013 Apr 25. Cancer Cell. 2013. PMID: 23623661 Free article.

7

Restoring the tumour suppressive function of p53 as a parallel strategy in melanoma therapy.

Lu M, Miller P, Lu X. Lu M, et al. Among authors: lu x. FEBS Lett. 2014 Aug 19;588(16):2616-21. doi: 10.1016/j.febslet.2014.05.008. Epub 2014 May 17. FEBS Lett. 2014. PMID: 24844434 Free article. Review.

8

A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway.

Lu M, Zak J, Chen S, Sanchez-Pulido L, Severson DT, Endicott J, Ponting CP, Schofield CJ, Lu X. Lu M, et al. Among authors: lu x. Cell. 2014 May 22;157(5):1130-45. doi: 10.1016/j.cell.2014.05.006. Cell. 2014. PMID: 24855949 Free article.

9

Cancer: pathological nuclear reprogramming?

Goding CR, Pei D, Lu X. Goding CR, et al. Among authors: lu x. Nat Rev Cancer. 2014 Aug;14(8):568-73. doi: 10.1038/nrc3781. Epub 2014 Jul 17. Nat Rev Cancer. 2014. PMID: 25030952 Review.

10

Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding.

Lu M, Muers MR, Lu X. Lu M, et al. Among authors: lu x. Nat Rev Mol Cell Biol. 2016 Aug;17(8):523-32. doi: 10.1038/nrm.2016.41. Epub 2016 May 25. Nat Rev Mol Cell Biol. 2016. PMID: 27220640 Review.

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