Fonseca-Berzal C - Search Results

1

Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi Y strain (DTU TcII): in vitro and in vivo studies.

Fonseca-Berzal C, da Silva CF, Batista DDGJ, de Oliveira GM, Cumella J, Batista MM, Peres RB, Silva da Gama Nefertiti A, Escario JA, Gómez-Barrio A, Arán VJ, Soeiro MNC. Fonseca-Berzal C, et al. Parasitology. 2020 Sep;147(11):1216-1228. doi: 10.1017/S0031182020000955. Epub 2020 Jun 12. Parasitology. 2020. PMID: 32530391 Free PMC article.

2

Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug.

Vega MC, Rolón M, Montero-Torres A, Fonseca-Berzal C, Escario JA, Gómez-Barrio A, Gálvez J, Marrero-Ponce Y, Arán VJ. Vega MC, et al. Eur J Med Chem. 2012 Dec;58:214-27. doi: 10.1016/j.ejmech.2012.10.009. Epub 2012 Oct 16. Eur J Med Chem. 2012. PMID: 23124218

3

Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase.

Fonseca-Berzal C, Merchán Arenas DR, Romero Bohórquez AR, Escario JA, Kouznetsov VV, Gómez-Barrio A. Fonseca-Berzal C, et al. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4851-6. doi: 10.1016/j.bmcl.2013.06.079. Epub 2013 Jul 12. Bioorg Med Chem Lett. 2013. PMID: 23899616

4

Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles.

Fonseca-Berzal C, Escario JA, Arán VJ, Gómez-Barrio A. Fonseca-Berzal C, et al. Parasitol Res. 2014 Mar;113(3):1049-56. doi: 10.1007/s00436-013-3740-5. Epub 2014 Jan 17. Parasitol Res. 2014. PMID: 24435615

5

In vitro phenotypic screening of 7-chloro-4-amino(oxy)quinoline derivatives as putative anti-Trypanosoma cruzi agents.

Fonseca-Berzal C, Rojas Ruiz FA, Escario JA, Kouznetsov VV, Gómez-Barrio A. Fonseca-Berzal C, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1209-13. doi: 10.1016/j.bmcl.2013.12.071. Epub 2014 Jan 9. Bioorg Med Chem Lett. 2014. PMID: 24461296

6

Development of novel benznidazole formulations: physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease.

Palmeiro-Roldán R, Fonseca-Berzal C, Gómez-Barrio A, Arán VJ, Escario JA, Torrado-Durán S, Torrado-Santiago S. Palmeiro-Roldán R, et al. Int J Pharm. 2014 Sep 10;472(1-2):110-7. doi: 10.1016/j.ijpharm.2014.06.015. Epub 2014 Jun 10. Int J Pharm. 2014. PMID: 24928135

7

Novel solid dispersions of benznidazole: preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system.

Fonseca-Berzal C, Palmeiro-Roldán R, Escario JA, Torrado S, Arán VJ, Torrado-Santiago S, Gómez-Barrio A. Fonseca-Berzal C, et al. Exp Parasitol. 2015 Feb;149:84-91. doi: 10.1016/j.exppara.2015.01.002. Epub 2015 Jan 9. Exp Parasitol. 2015. PMID: 25583295

8

Trypanocidal Activity of Long Chain Diamines and Aminoalcohols.

Legarda-Ceballos AL, del Olmo E, López-Abán J, Escarcena R, Bustos LA, Fonseca-Berzal C, Gómez-Barrio A, Dib JC, San Feliciano A, Muro A. Legarda-Ceballos AL, et al. Molecules. 2015 Jun 23;20(6):11554-68. doi: 10.3390/molecules200611554. Molecules. 2015. PMID: 26111182 Free PMC article.

9

Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.

Fonseca-Berzal C, Ibáñez-Escribano A, Reviriego F, Cumella J, Morales P, Jagerovic N, Nogal-Ruiz JJ, Escario JA, da Silva PB, Soeiro Mde N, Gómez-Barrio A, Arán VJ. Fonseca-Berzal C, et al. Eur J Med Chem. 2016 Jun 10;115:295-310. doi: 10.1016/j.ejmech.2016.03.036. Epub 2016 Mar 17. Eur J Med Chem. 2016. PMID: 27017556

10

Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes.

Fonseca-Berzal C, DA Silva CF, Menna-Barreto RF, Batista MM, Escario JA, Arán VJ, Gómez-Barrio A, Soeiro Mde N. Fonseca-Berzal C, et al. Parasitology. 2016 Sep;143(11):1469-78. doi: 10.1017/S0031182016001098. Epub 2016 Jun 17. Parasitology. 2016. PMID: 27312370

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