Chung NN - Search Results

1

Novel µ opioid antagonists derived from the µ opioid agonists endomorphin and [Dmt¹ ]DALDA (H-Dmt-D-Arg-Phe-Lys-NH₂ ).

Shi S, Xu J, Feng L, Fan X, Chen Z, Qin Y, Chung NN, Li T, Schiller PW. Shi S, et al. Among authors: chung nn. Chem Biol Drug Des. 2020 Nov;96(5):1305-1314. doi: 10.1111/cbdd.13743. Epub 2020 Aug 2. Chem Biol Drug Des. 2020. PMID: 32526055

2

Highly potent fluorescent analogues of the opioid peptide [Dmt1] DALDA.

Berezowska I, Chung NN, Lemieux C, Zelent B, Szeto HH, Schiller PW. Berezowska I, et al. Among authors: chung nn. Peptides. 2003 Aug;24(8):1195-200. doi: 10.1016/j.peptides.2003.07.004. Peptides. 2003. PMID: 14612191

3

Dansylated analogues of the opioid peptide [Dmt1]DALDA: in vitro activity profiles and fluorescence parameters.

Berezowska I, Lemieux C, Chung NN, Zelent B, Schiller PW. Berezowska I, et al. Among authors: chung nn. Acta Biochim Pol. 2004;51(1):107-13. Acta Biochim Pol. 2004. PMID: 15094830

4

Potent opioid peptide agonists containing 4'-[N-((4'-phenyl)-phenethyl)carboxamido]phenylalanine (Bcp) in place of Tyr.

Weltrowska G, Nguyen TM, Lemieux C, Chung NN, Schiller PW. Weltrowska G, et al. Among authors: chung nn. Chem Biol Drug Des. 2008 Nov;72(5):337-40. doi: 10.1111/j.1747-0285.2008.00720.x. Chem Biol Drug Des. 2008. PMID: 19012569

5

Cyclic opioid peptide agonists and antagonists obtained via ring-closing metathesis.

Berezowska I, Lemieux C, Chung NN, Wilkes BC, Schiller PW. Berezowska I, et al. Among authors: chung nn. Chem Biol Drug Des. 2009 Oct;74(4):329-34. doi: 10.1111/j.1747-0285.2009.00867.x. Epub 2009 Aug 20. Chem Biol Drug Des. 2009. PMID: 19694755 Free PMC article.

6

N-methylated cyclic enkephalin analogues retain high opioid receptor binding affinity.

Weltrowska G, Berezowska I, Lemieux C, Chung NN, Wilkes BC, Schiller PW. Weltrowska G, et al. Among authors: chung nn. Chem Biol Drug Des. 2010 Feb;75(2):182-8. doi: 10.1111/j.1747-0285.2009.00919.x. Epub 2009 Dec 17. Chem Biol Drug Des. 2010. PMID: 20028398 Free PMC article.

7

Bifunctional μ/δ opioid peptides: variation of the type and length of the linker connecting the two components.

Ding J, Lemieux C, Chung NN, Schiller PW. Ding J, et al. Among authors: chung nn. Chem Biol Drug Des. 2012 Feb;79(2):186-93. doi: 10.1111/j.1747-0285.2011.01268.x. Epub 2012 Jan 4. Chem Biol Drug Des. 2012. PMID: 22070627 Free PMC article.

8

Novel TIPP (H-Tyr-Tic-Phe-Phe-OH) analogues displaying a wide range of efficacies at the δ opioid receptor. Discovery of two highly potent and selective δ opioid agonists.

Berezowska I, Lemieux C, Chung NN, Ding J, Schiller PW. Berezowska I, et al. Among authors: chung nn. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1899-902. doi: 10.1016/j.bmcl.2012.01.063. Epub 2012 Jan 28. Bioorg Med Chem Lett. 2012. PMID: 22325949 Free PMC article.

9

N-terminal guanidinylation of TIPP (Tyr-Tic-Phe-Phe) peptides results in major changes of the opioid activity profile.

Weltrowska G, Nguyen TM, Chung NN, Wilkes BC, Schiller PW. Weltrowska G, et al. Among authors: chung nn. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5082-5. doi: 10.1016/j.bmcl.2013.07.036. Epub 2013 Jul 23. Bioorg Med Chem Lett. 2013. PMID: 23932788 Free PMC article.

10

[Dmt(1)]DALDA analogues with enhanced μ opioid agonist potency and with a mixed μ/κ opioid activity profile.

Bai L, Li Z, Chen J, Chung NN, Wilkes BC, Li T, Schiller PW. Bai L, et al. Among authors: chung nn. Bioorg Med Chem. 2014 Apr 1;22(7):2333-8. doi: 10.1016/j.bmc.2014.02.011. Epub 2014 Feb 19. Bioorg Med Chem. 2014. PMID: 24602401 Free PMC article.

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