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First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor.
Plummer R, Dua D, Cresti N, Drew Y, Stephens P, Foegh M, Knudsen S, Sachdev P, Mistry BM, Dixit V, McGonigle S, Hall N, Matijevic M, McGrath S, Sarker D. Plummer R, et al. Among authors: mcgonigle s. Br J Cancer. 2020 Aug;123(4):525-533. doi: 10.1038/s41416-020-0916-5. Epub 2020 Jun 11. Br J Cancer. 2020. PMID: 32523090 Free PMC article. Clinical Trial.
Neuropilin-1 drives tumor-specific uptake of chlorotoxin.
McGonigle S, Majumder U, Kolber-Simonds D, Wu J, Hart A, Noland T, TenDyke K, Custar D, Li D, Du H, Postema MHD, Lai WG, Twine NC, Woodall-Jappe M, Nomoto K. McGonigle S, et al. Cell Commun Signal. 2019 Jun 17;17(1):67. doi: 10.1186/s12964-019-0368-9. Cell Commun Signal. 2019. PMID: 31208428 Free PMC article.
Chronic social stress induces p16-mediated senescent cell accumulation in mice.
Lyons CE, Pallais JP, McGonigle S, Mansk RP, Collinge CW, Yousefzadeh MJ, Baker DJ, Schrank PR, Williams JW, Niedernhofer LJ, van Deursen JM, Razzoli M, Bartolomucci A. Lyons CE, et al. Among authors: mcgonigle s. Nat Aging. 2024 Nov 11. doi: 10.1038/s43587-024-00743-8. Online ahead of print. Nat Aging. 2024. PMID: 39528642
A key role for P2RX5 in brown adipocyte differentiation and energy homeostasis.
Razzoli M, McGonigle S, Sahu BS, Rodriguez P, Svedberg D, Rao L, Ruocco C, Nisoli E, Vezzani B, Frontini A, Bartolomucci A. Razzoli M, et al. Among authors: mcgonigle s. Adipocyte. 2024 Dec;13(1):2421745. doi: 10.1080/21623945.2024.2421745. Epub 2024 Nov 1. Adipocyte. 2024. PMID: 39484996 Free PMC article.
40 results