Kuriyan J - Search Results

1

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks.

Cofsky JC, Karandur D, Huang CJ, Witte IP, Kuriyan J, Doudna JA. Cofsky JC, et al. Among authors: kuriyan j. Elife. 2020 Jun 10;9:e55143. doi: 10.7554/eLife.55143. Elife. 2020. PMID: 32519675 Free PMC article.

2

Paul Sigler (1934-2000).

Jeruzalmi D, Kuriyan J, Doudna J. Jeruzalmi D, et al. Among authors: kuriyan j. Trends Biochem Sci. 2000 May;25(5):221-2. doi: 10.1016/s0968-0004(00)01587-5. Trends Biochem Sci. 2000. PMID: 10782089 Free article. No abstract available.

3

Molecular basis for multimerization in the activation of the epidermal growth factor receptor.

Huang Y, Bharill S, Karandur D, Peterson SM, Marita M, Shi X, Kaliszewski MJ, Smith AW, Isacoff EY, Kuriyan J. Huang Y, et al. Among authors: kuriyan j. Elife. 2016 Mar 28;5:e14107. doi: 10.7554/eLife.14107. Elife. 2016. PMID: 27017828 Free PMC article.

4

An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor.

Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. Shah NH, et al. Among authors: kuriyan j. Elife. 2016 Oct 4;5:e20105. doi: 10.7554/eLife.20105. Elife. 2016. PMID: 27700984 Free PMC article.

5

Deconstruction of the Ras switching cycle through saturation mutagenesis.

Bandaru P, Shah NH, Bhattacharyya M, Barton JP, Kondo Y, Cofsky JC, Gee CL, Chakraborty AK, Kortemme T, Ranganathan R, Kuriyan J. Bandaru P, et al. Among authors: kuriyan j. Elife. 2017 Jul 7;6:e27810. doi: 10.7554/eLife.27810. Elife. 2017. PMID: 28686159 Free PMC article.

6

Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.

Karandur D, Nawrotek A, Kuriyan J, Cherfils J. Karandur D, et al. Among authors: kuriyan j. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11416-11421. doi: 10.1073/pnas.1707970114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923919 Free PMC article.

7

A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.

Vercoulen Y, Kondo Y, Iwig JS, Janssen AB, White KA, Amini M, Barber DL, Kuriyan J, Roose JP. Vercoulen Y, et al. Among authors: kuriyan j. Elife. 2017 Sep 27;6:e29002. doi: 10.7554/eLife.29002. Elife. 2017. PMID: 28952923 Free PMC article.

8

Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen.

Shah NH, Löbel M, Weiss A, Kuriyan J. Shah NH, et al. Among authors: kuriyan j. Elife. 2018 Mar 16;7:e35190. doi: 10.7554/eLife.35190. Elife. 2018. PMID: 29547119 Free PMC article.

9

Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.

Kondo Y, Ognjenović J, Banerjee S, Karandur D, Merk A, Kulhanek K, Wong K, Roose JP, Subramaniam S, Kuriyan J. Kondo Y, et al. Among authors: kuriyan j. Science. 2019 Oct 4;366(6461):109-115. doi: 10.1126/science.aay0543. Epub 2019 Sep 19. Science. 2019. PMID: 31604311 Free PMC article.

10

Structural Insights into the Regulation of Ca²⁺/Calmodulin-Dependent Protein Kinase II (CaMKII).

Bhattacharyya M, Karandur D, Kuriyan J. Bhattacharyya M, et al. Among authors: kuriyan j. Cold Spring Harb Perspect Biol. 2020 Jun 1;12(6):a035147. doi: 10.1101/cshperspect.a035147. Cold Spring Harb Perspect Biol. 2020. PMID: 31653643 Free PMC article. Review.

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