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921 results

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Page 1
Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy.
Wang BZ, Morsink MA, Kim SW, Luo LJ, Zhang X, Soni RK, Lock RI, Rao J, Kim Y, Zhang A, Neyazi M, Gorham JM, Kim Y, Brown K, DeLaughter DM, Zhang Q, McDonough B, Watkins JM, Cunningham KM, Oudit GY, Fine BM, Seidman CE, Seidman JG, Vunjak-Novakovic G. Wang BZ, et al. Among authors: seidman jg. J Clin Invest. 2025 Jan 2;135(1):e181630. doi: 10.1172/JCI181630. J Clin Invest. 2025. PMID: 39744939 Free PMC article.
Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.
Kim Y, Kim SW, Saul D, Neyazi M, Schmid M, Wakimoto H, Slaven N, Lee JH, Layton OG, Wasson LK, Letendre JH, Xiao F, Ewoldt JK, Gkatzis K, Sommer P, Gobert B, Wiest-Daesslé N, McAfee Q, Singhal N, Lun M, Gorham JM, Arany Z, Sharma A, Toepfer CN, Oudit GY, Pu WT, Dickel DE, Pennacchio LA, Visel A, Chen CS, Seidman JG, Seidman CE. Kim Y, et al. Among authors: seidman jg. J Clin Invest. 2024 Dec 17:e183353. doi: 10.1172/JCI183353. Online ahead of print. J Clin Invest. 2024. PMID: 39688912 Free article.
Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice.
Kip P, Sluiter TJ, MacArthur MR, Tao M, Kruit N, Mitchell SJ, Jung J, Kooijman S, Gorham J, Seidman JG, Quax PHA, Decano JL, Aikawa M, Ozaki CK, Mitchell JR, de Vries MR. Kip P, et al. Among authors: seidman jg. Nat Commun. 2024 Nov 7;15(1):9652. doi: 10.1038/s41467-024-53844-8. Nat Commun. 2024. PMID: 39511181 Free PMC article.
Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling.
Ewoldt JK, Wang MC, McLellan MA, Cloonan PE, Chopra A, Gorham J, Li L, DeLaughter DM, Gao X, Lee JH, Willcox JAL, Layton O, Luu RJ, Toepfer CN, Eyckmans J, Seidman CE, Seidman JG, Chen CS. Ewoldt JK, et al. Among authors: seidman jg. Sci Adv. 2024 Oct 18;10(42):eadi6927. doi: 10.1126/sciadv.adi6927. Epub 2024 Oct 16. Sci Adv. 2024. PMID: 39413182 Free PMC article.
Author Correction: Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network.
Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Kulandaisamy A, Lu F, Keating EM, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Hill LD, Song MK, Trembley MA, Wang P, Gianeselli M, Prondzynski M, Bortolin RH, Bezzerides VJ, Chen K, Seidman JG, Seidman CE, Moskowitz IP, Pu WT. Sweat ME, et al. Among authors: seidman jg. Nat Cardiovasc Res. 2023 Nov;2(11):1095. doi: 10.1038/s44161-023-00373-0. Nat Cardiovasc Res. 2023. PMID: 39196102 No abstract available.
An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury.
Fleischer S, Nash TR, Tamargo MA, Lock RI, Venturini G, Morsink M, Graney PL, Li V, Lamberti MJ, Liberman M, Kim Y, Tavakol DN, Zhuang RZ, Whitehead J, Friedman RA, Soni RK, Seidman JG, Seidman CE, Geraldino-Pardilla L, Winchester R, Vunjak-Novakovic G. Fleischer S, et al. Among authors: seidman jg. Nat Cardiovasc Res. 2024 Sep;3(9):1123-1139. doi: 10.1038/s44161-024-00525-w. Epub 2024 Aug 15. Nat Cardiovasc Res. 2024. PMID: 39195859 Free PMC article.
921 results