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Investigational treatments for COVID-19 may increase ventricular arrhythmia risk through drug interactions.
medRxiv [Preprint]. 2020 May 26:2020.05.21.20109397. doi: 10.1101/2020.05.21.20109397.
medRxiv. 2020.
Update in:
CPT Pharmacometrics Syst Pharmacol. 2021 Feb;10(2):100-107. doi: 10.1002/psp4.12573.
PMID: 32511528
Free PMC article.
Updated.
Preprint.
Investigational Treatments for COVID-19 may Increase Ventricular Arrhythmia Risk Through Drug Interactions.
Varshneya M, Irurzun-Arana I, Campana C, Dariolli R, Gutierrez A, Pullinger TK, Sobie EA.
Varshneya M, et al.
CPT Pharmacometrics Syst Pharmacol. 2021 Feb;10(2):100-107. doi: 10.1002/psp4.12573. Epub 2021 Feb 11.
CPT Pharmacometrics Syst Pharmacol. 2021.
PMID: 33205613
Free PMC article.
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Slow Delayed Rectifier Current Protects Ventricular Myocytes From Arrhythmic Dynamics Across Multiple Species: A Computational Study.
Varshneya M, Devenyi RA, Sobie EA.
Varshneya M, et al.
Circ Arrhythm Electrophysiol. 2018 Oct;11(10):e006558. doi: 10.1161/CIRCEP.118.006558.
Circ Arrhythm Electrophysiol. 2018.
PMID: 30354408
Free PMC article.
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Prediction of arrhythmia susceptibility through mathematical modeling and machine learning.
Varshneya M, Mei X, Sobie EA.
Varshneya M, et al.
Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2104019118. doi: 10.1073/pnas.2104019118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34493665
Free PMC article.
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