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Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium.
Sajuthi SP, DeFord P, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak AC, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Among authors: wechsler me. bioRxiv [Preprint]. 2020 Apr 10:2020.04.09.034454. doi: 10.1101/2020.04.09.034454. bioRxiv. 2020. Update in: Nat Commun. 2020 Oct 12;11(1):5139. doi: 10.1038/s41467-020-18781-2 PMID: 32511326 Free PMC article. Updated. Preprint.
Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium.
Sajuthi SP, DeFord P, Li Y, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak ACY, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Among authors: wechsler me. Nat Commun. 2020 Oct 12;11(1):5139. doi: 10.1038/s41467-020-18781-2. Nat Commun. 2020. PMID: 33046696 Free PMC article.
Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma.
Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF Jr, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME; NHLBI AsthmaNet. Ortega VE, et al. Among authors: wechsler me. Lancet Child Adolesc Health. 2021 Dec;5(12):862-872. doi: 10.1016/S2352-4642(21)00268-6. Epub 2021 Nov 9. Lancet Child Adolesc Health. 2021. PMID: 34762840 Free PMC article.
Race is associated with differences in airway inflammation in patients with asthma.
Nyenhuis SM, Krishnan JA, Berry A, Calhoun WJ, Chinchilli VM, Engle L, Grossman N, Holguin F, Israel E, Kittles RA, Kraft M, Lazarus SC, Lehman EB, Mauger DT, Moy JN, Peters SP, Phipatanakul W, Smith LJ, Sumino K, Szefler SJ, Wechsler ME, Wenzel S, White SR, Ackerman SJ. Nyenhuis SM, et al. Among authors: wechsler me. J Allergy Clin Immunol. 2017 Jul;140(1):257-265.e11. doi: 10.1016/j.jaci.2016.10.024. Epub 2017 Jan 6. J Allergy Clin Immunol. 2017. PMID: 28069248 Free PMC article. Clinical Trial.
Novel Treatments for Airway Disease.
Wechsler ME, Akuthota P, Khoury P. Wechsler ME, et al. N Engl J Med. 2017 Aug 10;377(6):597-8. doi: 10.1056/NEJMc1708004. N Engl J Med. 2017. PMID: 28792869 No abstract available.
PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment.
Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A. Israel E, et al. Among authors: wechsler me. J Allergy Clin Immunol. 2021 May;147(5):1594-1601. doi: 10.1016/j.jaci.2021.01.037. Epub 2021 Mar 2. J Allergy Clin Immunol. 2021. PMID: 33667479 Free PMC article.
297 results