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Page 1
Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels.
Wang Z, Chen H, Bartz TM, Bielak LF, Chasman DI, Feitosa MF, Franceschini N, Guo X, Lim E, Noordam R, Richard MA, Wang H, Cade B, Cupples LA, de Vries PS, Giulanini F, Lee J, Lemaitre RN, Martin LW, Reiner AP, Rich SS, Schreiner PJ, Sidney S, Sitlani CM, Smith JA, Willems van Dijk K, Yao J, Zhao W, Fornage M, Kardia SLR, Kooperberg C, Liu CT, Mook-Kanamori DO, Province MA, Psaty BM, Redline S, Ridker PM, Rotter JI, Boerwinkle E, Morrison AC; CHARGE Gene-Lifestyle Interactions Working Group. Wang Z, et al. Among authors: wang h. Circ Genom Precis Med. 2020 Aug;13(4):e002772. doi: 10.1161/CIRCGEN.119.002772. Epub 2020 Jun 8. Circ Genom Precis Med. 2020. PMID: 32510982 Free PMC article.
Whole genome sequence analysis of serum amino acid levels.
Yu B, de Vries PS, Metcalf GA, Wang Z, Feofanova EV, Liu X, Muzny DM, Wagenknecht LE, Gibbs RA, Morrison AC, Boerwinkle E. Yu B, et al. Among authors: wang z. Genome Biol. 2016 Nov 24;17(1):237. doi: 10.1186/s13059-016-1106-x. Genome Biol. 2016. PMID: 27884205 Free PMC article.
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent.
Smith CE, Follis JL, Dashti HS, Tanaka T, Graff M, Fretts AM, Kilpeläinen TO, Wojczynski MK, Richardson K, Nalls MA, Schulz CA, Liu Y, Frazier-Wood AC, van Eekelen E, Wang C, de Vries PS, Mikkilä V, Rohde R, Psaty BM, Hansen T, Feitosa MF, Lai CQ, Houston DK, Ferruci L, Ericson U, Wang Z, de Mutsert R, Oddy WH, de Jonge EAL, Seppälä I, Justice AE, Lemaitre RN, Sørensen TIA, Province MA, Parnell LD, Garcia ME, Bandinelli S, Orho-Melander M, Rich SS, Rosendaal FR, Pennell CE, Kiefte-de Jong JC, Kähönen M, Young KL, Pedersen O, Aslibekyan S, Rotter JI, Mook-Kanamori DO, Zillikens MC, Raitakari OT, North KE, Overvad K, Arnett DK, Hofman A, Lehtimäki T, Tjønneland A, Uitterlinden AG, Rivadeneira F, Franco OH, German JB, Siscovick DS, Cupples LA, Ordovás JM. Smith CE, et al. Among authors: wang z, wang c. Mol Nutr Food Res. 2018 Feb;62(3):10.1002/mnfr.201700347. doi: 10.1002/mnfr.201700347. Epub 2017 Dec 11. Mol Nutr Food Res. 2018. PMID: 28941034 Free PMC article.
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Jakupović H, Chasman DI, Manning A, Ntalla I, Aschard H, Brown MR, de las Fuentes L, Franceschini N, Guo X, Vojinovic D, Aslibekyan S, Feitosa MF, Kho M, Musani SK, Richard M, Wang H, Wang Z, Bartz TM, Bielak LF, Campbell A, Dorajoo R, Fisher V, Hartwig FP, Horimoto ARVR, Li C, Lohman KK, Marten J, Sim X, Smith AV, Tajuddin SM, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Graff M, Harris SE, He M, Hsu FC, Jackson AU, Zhao JH, Kraja AT, Kühnel B, Laguzzi F, Lyytikäinen LP, Nolte IM, Rauramaa R, Riaz M, Robino A, Rueedi R, Stringham HM, Takeuchi F, van der Most PJ, Varga TV, Verweij N, Ware EB, Wen W, Li X, Yanek LR, Amin N, Arnett DK, Boerwinkle E, Brumat M, Cade B, Canouil M, Chen YI, Concas MP, Connell J, de Mutsert R, de Silva HJ, de Vries PS, Demirkan A, Ding J, Eaton CB, Faul JD, Friedlander Y, Gabriel KP, Ghanbari M, Giulianini F, Gu CC, Gu D, Harris TB, He J, Heikkinen S, Heng CK, Hunt SC, Ikram MA, Jonas JB, Koh WP, Komulainen P, Krieger JE, Kritchevsky SB, Kutalik Z, Kuusisto J, Langefeld CD, Langenberg C, Launer LJ, Leander K, Lemaitre RN, Lewis CE, Liang … See abstract for full author list ➔ Kilpeläinen TO, et al. Among authors: wang h, wang yx, wang z. Nat Commun. 2019 Jan 22;10(1):376. doi: 10.1038/s41467-018-08008-w. Nat Commun. 2019. PMID: 30670697 Free PMC article.
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li C, Feitosa MF, Richard MA, Noordam R, Aschard H, Bartz TM, Bielak LF, Deng X, Dorajoo R, Lohman KK, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Evangelou E, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kasturiratne A, Komulainen P, Kühnel B, Laguzzi F, Lee JH, Luan J, Lyytikäinen LP, Matoba N, Nolte IM, Pietzner M, Riaz M, Said MA, Scott RA, Sofer T, Stančáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang Y, Ware EB, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Amin N, Amini M, Arking DE, Aung T, Ballantyne C, Boerwinkle E, Broeckel U, Campbell A, Canouil M, Charumathi S, Chen YI, Connell JM, de Faire U, de las Fuentes L, de Mutsert R, de Silva HJ, Ding J, Dominiczak AF, Duan Q, Eaton CB, Eppinga RN, Faul JD, Fisher V, Forrester T, Franco OH, Friedlander Y, Ghanbari M, Giulianini F, Grabe HJ, Grove ML, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Howard BV, Ikram MA; In… See abstract for full author list ➔ de Vries PS, et al. Among authors: wang l, wang yx, wang z, wang y. Am J Epidemiol. 2019 Jun 1;188(6):1033-1054. doi: 10.1093/aje/kwz005. Am J Epidemiol. 2019. PMID: 30698716 Free PMC article.
Metabolomic Pattern Predicts Incident Coronary Heart Disease.
Wang Z, Zhu C, Nambi V, Morrison AC, Folsom AR, Ballantyne CM, Boerwinkle E, Yu B. Wang Z, et al. Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1475-1482. doi: 10.1161/ATVBAHA.118.312236. Epub 2019 May 16. Arterioscler Thromb Vasc Biol. 2019. PMID: 31092011 Free PMC article.
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.
Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ, Schwander K, Cade BE, Manning A, Aschard H, Brown MR, Chen H, Franceschini N, Musani SK, Richard M, Vojinovic D, Aslibekyan S, Bartz TM, de las Fuentes L, Feitosa M, Horimoto AR, Ilkov M, Kho M, Kraja A, Li C, Lim E, Liu Y, Mook-Kanamori DO, Rankinen T, Tajuddin SM, van der Spek A, Wang Z, Marten J, Laville V, Alver M, Evangelou E, Graff ME, He M, Kühnel B, Lyytikäinen LP, Marques-Vidal P, Nolte IM, Palmer ND, Rauramaa R, Shu XO, Snieder H, Weiss S, Wen W, Yanek LR, Adolfo C, Ballantyne C, Bielak L, Biermasz NR, Boerwinkle E, Dimou N, Eiriksdottir G, Gao C, Gharib SA, Gottlieb DJ, Haba-Rubio J, Harris TB, Heikkinen S, Heinzer R, Hixson JE, Homuth G, Ikram MA, Komulainen P, Krieger JE, Lee J, Liu J, Lohman KK, Luik AI, Mägi R, Martin LW, Meitinger T, Metspalu A, Milaneschi Y, Nalls MA, O'Connell J, Peters A, Peyser P, Raitakari OT, Reiner AP, Rensen PCN, Rice TK, Rich SS, Roenneberg T, Rotter JI, Schreiner PJ, Shikany J, Sidney SS, Sims M, Sitlani CM, Sofer T, Strauch K, Swertz MA, Taylor KD, Uitterlinden AG, van Duijn CM, Völzke H, Waldenberger M, Wallance RB, van Dijk KW, Yu C, … See abstract for full author list ➔ Noordam R, et al. Among authors: wang h, wang z. Nat Commun. 2019 Nov 12;10(1):5121. doi: 10.1038/s41467-019-12958-0. Nat Commun. 2019. PMID: 31719535 Free PMC article.
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood.
Kurniansyah N, Goodman MO, Kelly TN, Elfassy T, Wiggins KL, Bis JC, Guo X, Palmas W, Taylor KD, Lin HJ, Haessler J, Gao Y, Shimbo D, Smith JA, Yu B, Feofanova EV, Smit RAJ, Wang Z, Hwang SJ, Liu S, Wassertheil-Smoller S, Manson JE, Lloyd-Jones DM, Rich SS, Loos RJF, Redline S, Correa A, Kooperberg C, Fornage M, Kaplan RC, Psaty BM, Rotter JI, Arnett DK, Morrison AC, Franceschini N, Levy D; NHLBI Trans-Omics in Precision Medicine (TOPMed) Consortium; Sofer T. Kurniansyah N, et al. Among authors: wang z. Nat Commun. 2022 Jun 21;13(1):3549. doi: 10.1038/s41467-022-31080-2. Nat Commun. 2022. PMID: 35729114 Free PMC article.
Rare genetic variants explain missing heritability in smoking.
Jang SK, Evans L, Fialkowski A, Arnett DK, Ashley-Koch AE, Barnes KC, Becker DM, Bis JC, Blangero J, Bleecker ER, Boorgula MP, Bowden DW, Brody JA, Cade BE, Jenkins BWC, Carson AP, Chavan S, Cupples LA, Custer B, Damrauer SM, David SP, de Andrade M, Dinardo CL, Fingerlin TE, Fornage M, Freedman BI, Garrett ME, Gharib SA, Glahn DC, Haessler J, Heckbert SR, Hokanson JE, Hou L, Hwang SJ, Hyman MC, Judy R, Justice AE, Kaplan RC, Kardia SLR, Kelly S, Kim W, Kooperberg C, Levy D, Lloyd-Jones DM, Loos RJF, Manichaikul AW, Gladwin MT, Martin LW, Nouraie M, Melander O, Meyers DA, Montgomery CG, North KE, Oelsner EC, Palmer ND, Payton M, Peljto AL, Peyser PA, Preuss M, Psaty BM, Qiao D, Rader DJ, Rafaels N, Redline S, Reed RM, Reiner AP, Rich SS, Rotter JI, Schwartz DA, Shadyab AH, Silverman EK, Smith NL, Smith JG, Smith AV, Smith JA, Tang W, Taylor KD, Telen MJ, Vasan RS, Gordeuk VR, Wang Z, Wiggins KL, Yanek LR, Yang IV, Young KA, Young KL, Zhang Y, Liu DJ, Keller MC, Vrieze S. Jang SK, et al. Among authors: wang z. Nat Hum Behav. 2022 Nov;6(11):1577-1586. doi: 10.1038/s41562-022-01408-5. Epub 2022 Aug 4. Nat Hum Behav. 2022. PMID: 35927319 Free PMC article.
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